How do you prepare GIK infusion?

How do you prepare GIK infusion?

GIK solution(*) is prepared as a mixture of 500 mL 5% dextrose, 10 IU short-acting insulin and 10 mmol K (1 ampoule of 7.5% KCl). The infusion is started at 08:00-09:00 am in the day of surgery. The infusion rate is started at 100 mL/h. The infusion is renewed in every 5 hours.

What is a GIK infusion?

The rationale for use of glucose/insulin/potassium (GIK) infusions is to maintain normal glucose levels, stimulate potassium uptake, suppress free-fatty acid metabolism and enhance glycolysis in the ischaemic myocardium.

When do you stop GKI infusion?

If blood glucose is less than 3 mmol/l at any stage, or the patient has symptomatic hypoglycaemia, discontinue GKI and commence 10% glucose at 100ml/hr until blood glucose greater than 5 mmol/l; GKI may then be recommenced with appropriate adjustment of insulin dose.

When is Albertis regimen used?

The recommendations for type 1 diabetic patients were to use the Alberti regimen in all patients undergoing surgery and to continue the infusion until the patient was eating (ambulatory surgery was in its infancy in 1979). Practical aspects of the use of the combined regimen were discussed in detail.

How do you give GIK?

GIK infusion: 500 cc glucose 5% with insulin and 10 mmol KCL per 500 cc. Start at 83 ml/hr….

1. Day before surgery: half evening dose long acting insulin.
2. Day of surgery:
3. Measure blood glucose every 60 minutes, start 30 min prior to surgery.

What type of insulin is used for GKI?

The GKI consisted of 16 U human soluble insulin and 20 mmol potassium chloride in 500 mL 10% glucose. Blood glucose was measured every 2 hours with Boehringer Mannheim Glycaemie test strips, pulse and blood pressure were measured every 4 hours, and plasma glucose samples were taken every 8 hours.

What is GIK regime?

(GIK regime) a method for controlling blood-sugar levels in diabetic patients who are being fasted for whatever reason. It involves infusing a solution of glucose (G), insulin (I), and potassium (K) chloride intravenously over a standard time period.

What is GIK diabetes?

Glucosa-Insulin-Potassium (GIK) solution used with diabetic patients provides better recovery after coronary bypass operations.

Which IV fluid is best for diabetic patients?

For decades, 0.9% saline has been the fluid of choice for diabetic ketoacidosis, and its use continues to be advocated in modern textbooks on diabetes. Early studies on diabetic ketoacidosis in the 1970s used 0.9% saline,5 and this approach was reinforced a decade later.

Can you give 5 dextrose to diabetics?

Dextrose should be carefully given to people who have diabetes, because they might not be able to process dextrose as quickly as would someone without the condition. Dextrose can increase the blood sugar too much, which is known as hyperglycemia.

What is modified Albertis regimen?

What is GIK solution?

How is glucose potassium insulin ( GKI ) administered?

Glucose potassium insulin (GKI) infusion – This is an alternative regime where 500ml of 10 per cent dextrose, 10mmol potassium chloride and 10 units of insulin are all given in the same infusion at a rate of 100ml/hour. CBG levels should be measured hourly to ensure the glucose remains within the target of 7-11mmol/l.

What kind of insulin is used in GIK?

The GIK regimen is composed of: 1. 10% Dextrose 500 ml 2. 10 Units Short acting (Regular) Insulin This is started at the rate of 100 ml/hour (i.e. 2 Units/hr of Insulin and 10 grams of Dextrose). This regimen is for blood glucose level upto 10 mmol (180 mg/dl).

When to put a patient on a GIK regimen?

Put patient on GIK (Glucose-Insulin-Potassium) regimen according to blood sugar level at least one hour before starting surgery. The GIK regimen should continue at least one hour after the patient has taken the first post operative meal.

How is GIK used in the treatment of sepsis?

Recently, this composition has also been used for management of Acute Myocardial Infarction and Severe Sepsis as well. By supplying glucose, the need for protein catabolism to meet gluconeogenic needs in the diabetic patient is reduced leading to less negative nitrogen balance.