How often can 8mg Zofran be taken?

How often can 8mg Zofran be taken?

The recommended oral dose is 8mg taken 1 to 2 hours before chemotherapy or radiation treatment, followed by 8 mg every 12 hours for a maximum of 5 days to protect against delayed or prolonged emesis.

How frequently can you take Zofran?

Ondansetron may be taken up to 3 times a day for 1 to 2 days after your chemotherapy or radiation treatment is finished. If you are taking this medication on a prescribed schedule, take it regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.

How is ondansetron distributed?

Ondansetron is widely distributed (volume of distribution approximately 160L) and binds moderately (70 to 76%) to plasma proteins; the elimination half-life averages approximately 3.8 +/- 1 hours. Clearance occurs by hepatic metabolism (95%) rather than renal excretion.

Can you take Zofran 8mg every 6 hours?

You may take one 8 mg tablet every 6 hours. If your nausea does not ease by 30 minutes after taking Zofran, take medicine #2, prochlorperazine (Compazine). Zofran will not make you sleepy. Rare side effects include headache, constipation, or diarrhea.

Can I take 8 mg of Zofran?

Adults typically take one 8-mg tablet or rapidly disintegrating tablet or 10 mL of liquid twice a day. For patients ages 12 and older, the dosage is the same as for adults. For those ages 4 to 11, patients should take a 4-mg tablet or rapidly disintegrating tablet or 5 mL of liquid three times per day.

Can you take 8 mg of Zofran while pregnant?

Typical dosage for pregnancy nausea The dose of Zofran for hyperemesis gravidarum requiring hospitalization is a maximum of 10 milligrams via intravenous therapy (IV) every 8 hours. More typical pregnancy nausea is managed by a much lower oral dose — 4 to 8 mg every 8 hours.

How do you administer Zofran?

The recommended adult intravenous dosage of ZOFRAN is 4 mg undiluted administered intravenously in not less than 30 seconds, preferably over 2 to 5 minutes, immediately before induction of anesthesia, or postoperatively if the patient did not receive prophylactic antiemetics and experiences nausea and/or vomiting …

What is the half life of IV Zofran?

The disposition of ondansetron following oral, intramuscular and intravenous dosing in adults is similar with a terminal half life of about 3 hours and steady state volume of distribution of about 140 L. Equivalent systemic exposure is achieved after intramuscular and intravenous administration of ondansetron.

Can I take Zofran every 8 hours?

For prevention of nausea and vomiting after radiation treatment: Adults—At first, 8 milligrams (mg) taken 1 to 2 hours before radiation treatment. Then, the dose is 8 mg every 8 hours.

How do I take ondansetron 8mg tablet?

How should I take ondansetron?

1. Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil.
2. Use dry hands to remove the tablet and place it in your mouth.
3. Do not swallow the tablet whole.
4. Swallow several times as the tablet dissolves.

Does Zofran make you sleepy?

Zofran may cause headaches, drowsiness, constipation and other mild side effects. In rare cases, the anti-nausea medication can cause erratic heartbeats and high serotonin levels, which may be life-threatening.

How much Ondansetron is in 5 ml of Zofran?

Each 5 mL of ZOFRAN Oral Solution contains 5 mg of ondansetron HCl dihydrate equivalent to 4 mg of ondansetron. ZOFRAN Oral Solution contains the inactive ingredients citric acid anhydrous, purified water, sodium benzoate, sodium citrate, sorbitol, and strawberry flavor.

How many Zofran 4 mg tablets are there?

ZOFRAN Tablets, 4 mg (ondansetron HCl dihydrate equivalent to 4 mg of ondansetron), are white, oval, film-coated tablets engraved with “Zofran” on one side and “4” on the other in daily unit dose packs of 3 tablets (NDC 0173-0446-04), bottles of 30 tablets (NDC 0173-0446-00), and unit dose packs of 100 tablets (NDC 0173-0446-02).

When to take Zofran 8 mg before or after chemotherapy?

8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose. Then administer 8 mg twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy.

How many milligrams of Zofran should a 6 month old take?

Subsequent doses (0.15 mg/kg up to a maximum of 16 mg per dose) are administered 4 and 8 hours after the first dose of ZOFRAN. For pediatric patients aged 6 months through 18 years, the intravenous dosage of ZOFRAN is three 0.15-mg/kg doses up to a maximum of 16 mg per dose [see Clinical Studies, CLINICAL PHARMACOLOGY ].