What causes macular pucker?
Most macular pucker is related to aging, but it can also be caused by other eye conditions. These include detached retina, inflammation of the eye (uveitis), and diabetic retinopathy. A macular pucker can be caused by trauma from eye surgery or eye injury as well.
What is macular pucker?
Occasionally, an injury or medical condition creates strands of scar tissue inside the eye. These are called epiretinal membranes, and they can pull on the macula, leading to a distortion in vision. When this pulling makes the macula wrinkle, it is called macular pucker.
What is vitreomacular adhesion?
Share: Michael Trese, MD: Vitreomacular adhesion (VMA) is a condition when the vitreous gel adheres in an abnormally strong manner to the retina. VMA can lead to vitreomacular traction (VMT) and subsequent loss or distortion (metamorphopsia) of visual acuity, a condition known as symptomatic VMA.
Does macular pucker get better?
On average, about half of the vision lost from a macular pucker is restored; some people have significantly more vision restored, some less. In most cases, vision distortion is significantly reduced. Recovery of vision can take up to three months.
Does macular pucker go away?
Macular pucker surgery addresses macular pucker, a condition in which scar tissue (called an epiretinal membrane, or ERM) forms on the retina. This condition is frequently age-related, slow-progressing, and can even go away on its own.
Does macular pucker improve itself?
Sometimes the scar tissue that causes the macular pucker separates from the retina, and the macular pucker heals on its own. If you notice a change in your vision, it’s important to contact your eye doctor right away.
Is vitreomacular adhesion normal?
Vitreomacular adhesion (VMA) can be serious, but it’s treatable. It involves two parts of your eye. One is the vitreous, or the “jelly” part that fills the eyeball. The other is the macula, a small area on the retina responsible for the central part of your field of vision.
Can a macular pucker repair itself?
Will macular pucker heal itself?
When should you have macular pucker surgery?
Benefits of macular pucker surgery If the vision problems from a macular pucker start to interfere with your daily activities like reading and driving, you may consider surgery. Eyedrops, supplements, or medication can’t help macular pucker-related vision loss.
How many eyes have been treated with ocriplasmin?
Overall, 652 eyes were treated: 464 with ocriplasmin and 188 with placebo. Vitreomacular adhesion resolved in 26.5% of ocriplasmin-injected eyes and in 10.1% of placebo-injected eyes (P<0.001).
Are there any phase 3 studies for ocriplasmin?
We performed two multicenter, randomized, double-blind, placebo-controlled, phase 3 studies (TG-MV-006 and TG-MV-007, hereafter called study 006 and study 007) to test the efficacy and safety of a single intravitreal injection of ocriplasmin. Patients were randomly assigned to intravitreal injection of either ocriplasmin or placebo.
Are there any adverse events with ocriplasmin injections?
Ocular adverse events (e.g., vitreous floaters, photopsia, or injection-related eye pain — all self-reported — or conjunctival hemorrhage) occurred in 68.4% of ocriplasmin-injected eyes and in 53.5% of placebo-injected eyes (P<0.001), and the incidence of serious ocular adverse events was similar in the two groups (P=0.26).
Is the microplasmin study sponsored by ThromboGenics?
Both trials were designed, coordinated, and sponsored by ThromboGenics. The data were gathered independently by the Microplasmin for Intravitreous Injection — Traction Release without Surgical Treatment (MIVI-TRUST) study groups and were analyzed by contract research organizations paid by ThromboGenics.