Does Chlamydia trachomatis cause lymphogranuloma venereum?
LGV is a long-term (chronic) infection of the lymphatic system. It is caused by any of three different types (serovars) of the bacteria Chlamydia trachomatis. The bacteria are spread by sexual contact. The infection is not caused by the same bacteria that cause genital chlamydia.
Which of the following cells is are commonly attacked by Chlamydia trachomatis in LGV infection?
81.1). The mucosal epithelial cells are the primary target cell type in vivo. For most C. trachomatis strains, infection is limited to the mucous membrane, although lymphogranuloma venereum (LGV) strains attack deep lymphatic tissues.
What are serovars of chlamydia?
Chlamydia trachomatis serovars A-C infect conjunctival epithelial cells and untreated infection can lead to blindness. D-K infect genital tract epithelial cells resulting in pelvic inflammatory disease, ectopic pregnancy, and sterility while L1-L3 infect epithelial cells and macrophages, causing an invasive infection.
What is lymphogranuloma venereum LGV?
Lymphogranuloma venereum (LGV) is an ulcerative disease of the genital area.[1] Its cause is the gram-negative bacteria Chlamydia trachomatis, especially serovars L1, L2, and L3.[2] It is an uncommon, sexually transmitted infection. It is transmittable by vaginal, oral or anal sex.
Is LGV treatable?
Treatment for LGV (Lymphogranuloma Venereum) LGV can be treated with three weeks of antibiotics. CDC STD Treatment Guidelines recommend the use of doxycyline, twice a day for 21 days. An alternative treatment is erythromycin base or azithromycin.
How does Chlamydia trachomatis affect the body?
Chlamydia is an infection by the bacteria Chlamydia trachomatis (C. trachomatis). Chlamydia infection can affect several organs, including the penis, vagina, cervix, urethra, anus, eye, and throat. It can cause severe and sometimes permanent damage to the reproductive system.
What cells does Chlamydia trachomatis infect?
The primary targets of C. trachomatis are epithelial cells of the urogenital tract and conjunctiva (6), which are able to present pathogenic antigens via major histocompatibility complex class I (MHC I) molecules (7).
What is the shape of Chlamydia trachomatis?
Pathogen name and classification Chlamydia trachomatis(C. trachomatis)is a Gram-negative coccoid or rod-shaped bacteria that causes genitourinary tract and eye infections.
What are the different types of Chlamydia trachomatis?
Sexually transmitted disease caused by Chlamydia trachomatis, an intracellular bacteria Different genovars produce specific clinical manifestations; i.e. types A, B, Ba and C cause trachoma, types LGV I, II and III (serovars L1, L2 and L3) cause LGV and types D to K cause oculogenital diseases
What kind of disease is Chlamydia venereum ( LGV )?
Lymphogranuloma Venereum (LGV) Lymphogranuloma venereum (LGV) is a disease caused by 3 unique strains of Chlamydia trachomatis and characterized by a small, often asymptomatic skin lesion, followed by regional lymphadenopathy in the groin or pelvis. Alternatively, if acquired by anal sex, it may manifest as severe proctitis.
What causes lymphogranuloma venereum ( LGV )?
Lymphogranuloma Venereum (LGV) LGV is caused by serotypes L1, L2, and L3 of the bacteria Chlamydia trachomatis. These serotypes differ from the chlamydial serotypes that cause trachoma, inclusion conjunctivitis, and chlamydial urethritis and cervicitis because they can invade and reproduce in regional lymph nodes.
Where does LGV occur in the human body?
These serotypes differ from the chlamydial serotypes that cause trachoma, inclusion conjunctivitis, and chlamydial urethritis and cervicitis because they can invade and reproduce in regional lymph nodes. LGV occurs sporadically in the US but is endemic in parts of Africa, India, Southeast Asia, South America, and the Caribbean.