What are horizontal cells and amacrine cells?

What are horizontal cells and amacrine cells?

Amacrine cells and horizontal cells are two types of interneurons in the retina that are primarily responsible for lateral interactions within the retina. Amacrine cells receive inputs from bipolar cells while horizontal cells receive inputs from photoreceptors.

What does amacrine cells do in the retina?

The AII amacrine cells are the major carriers of rod signals to the ganglion cells in the retina. As such, they play a role in speeding up the slow potential rod messages for presentation to ganglion cells (18, 31). Their distribution in the retina suggests that they tile the complete retina (32).

Which retinal layer has amacrine and horizontal cells?

Inner nuclear layer
Inner nuclear layer This layer of the retina contains the cell bodies of bipolar cells, horizontal cells, and amacrine cells.

What is the function of the horizontal bipolar and amacrine cells of the eye?

Horizontal Cells and amacrine cells perform intermediate and lateral processing by integrating information at the bipolar and ganglion cell layers, respectively.

What are horizontal cells of retina?

Horizontal cells are the laterally interconnecting neurons having cell bodies in the inner nuclear layer of the retina of vertebrate eyes. They help integrate and regulate the input from multiple photoreceptor cells.

Where are amacrine cell bodies located?

the retina
Location. Amacrine cells have their cell bodies located in the inner nuclear layer of the retina and have projections in the inner plexiform layer.

Where are horizontal cells in retina?

What cells in retina are linked by horizontal cells?

Horizontal cells (HCs) and amacrine cells (ACs), two types of retinal interneurons, modulate the information flow from photoreceptors (PRs) to bipolar cells (BCs) in the outer plexiform layer (OPL) and from BCs to retinal ganglion cells (RGCs) in the inner plexiform layer (IPL), respectively.

What is the function of the horizontal cells?

Horizontal cells receive excitatory input from photoreceptors and provide feedback inhibition to photoreceptors and feedforward inhibition to bipolar cells.

Where are amacrine cells located in the retina?

Amacrine cells are a type of interneuron in the retina involved in the retina’s indirect pathway. Their cell bodies are located in the inner nuclear layer. They operate at the inner plexiform layer. Amacrine cells receive inputs from bipolar cells, and then connect bipolar cells to ganglion cells.

How are amacrine cells different from horizontal cells?

Amacrine cells and horizontal cells are two types of interneurons in the retina that are primarily responsible for lateral interactions within the retina. Amacrine cells receive inputs from bipolar cells while horizontal cells receive inputs from photoreceptors.

Where are horizontal cells located in the retina?

Horizontal cells are a type of interneurons in the retina that work laterally similar to amacrine cells. Their cell bodies are also located in the inner nuclear layer and they operate at the outer plexiform layer. Horizontal cells receive inputs from multiple photoreceptors.

Which is the most studied cell in the retina?

GABAergic amacrine cells, in particular, typically make reciprocal synapses with bipolar cells. A17 is the most well studied of the GABAergic reciprocal amacrine cells in the retina and we shall return to this cell later.

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