What does the PER3 gene do?
UniProtKB/Swiss-Prot Summary for PER3 Gene The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior.
Where is the promoter of the period gene?
Period (per) is a gene located on the X chromosome of Drosophila melanogaster.
What is CRY1 gene?
CRY1 (Cryptochrome Circadian Regulator 1) is a Protein Coding gene. Diseases associated with CRY1 include Delayed Sleep Phase Disorder and Sleep Disorder. Among its related pathways are Melatonin metabolism and effects and Circadian rythm related genes.
What is DSPS sleep disorder?
Delayed sleep phase syndrome (DSPS) is a disorder in which a person’s sleep is delayed by two hours or more beyond what is considered an acceptable or conventional bedtime. The delayed sleep then causes difficulty in being able to wake up at the desired time.
Why is the period gene linked to the luciferase gene?
Why is the luciferase gene such a popularly used reporter gene in experiments? Luciferase has a short half-life and can convert the chemical luciferin into light. the period gene is linked to the luciferase gene.
What can a mutation in the period gene alter in a fly?
The findings of this study suggest that period mutations influence ethanol induced behavior and ethanol metabolism in Drosophila and that flies with longer circadian periods are more sensitive to ethanol exposure.
What is the difference between CRY1 and CRY2?
The two members of the Arabidopsis cryptochrome gene family (CRY1 and CRY2) overlap in function, but their proteins differ in stability: cry2 is rapidly degraded under light fluences (green, blue, and UV) that activate the photoreceptor, but cry1 is not.
What is Dspd?
Delayed sleep-wake phase syndrome, or delayed sleep-wake phase disorder (DSPD), is characterized by the inability to fall asleep, difficulty waking up on time1, and, in some cases, daytime sleepiness or depression2.
How is luciferase affected by temperature?
When firefly luciferase is mixed with luciferin and ATP, a transient flash of light is produced, followed by a weak light, lasting hours. When pressurized below the temperature optimum, pressure decreased the light intensity, while increasing it above the temperature optimum.