How does moxifloxacin treat pneumonia?

How does moxifloxacin treat pneumonia?

Study medication Moxifloxacin contains a C-8 methoxy substitute that increases bactericidal activity, decreases the risk of selecting resistant mutants, and enhances activity against Gram-positive bacteria [47].

What is Avelox used to cure?

Avelox is used to treat different types of bacterial infections of the skin, sinuses, lungs, or stomach. It is used to treat community acquired pneumonia, plague, bacterial sinusitis, and chronic bronchitis with bacterial infection.

Does Avelox treat pneumonia?

AVELOX is indicated in adult patients for the treatment of Community Acquired Pneumonia caused by susceptible isolates of Streptococcus pneumoniae (including multi-drug resistant Streptococcus pneumoniae [MDRSP]), Haemophilus influenzae, Moraxella catarrhalis, methicillin-susceptible Staphylococcus aureus, Klebsiella …

Is Avelox good for bronchitis?

AVELOX is indicated in adult patients for the treatment of Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) caused by susceptible isolates of Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, methicillin-susceptible Staphylococcus aureus, or Moraxella …

How long does moxifloxacin stay in your body?

The elimination half-life of moxifloxacin is 11.5 to 15.6 hours (single-dose, oral). About 45% of an oral or intravenous dose of moxifloxacin is excreted as unchanged drug (about 20% in urine and 25% in feces).

What STD does moxifloxacin treat?

Moxifloxacin was shown to be an active drug against Chlamydia spp., at least in vitro, with MICs ranging from 0.03 to 0.125 mg/L, at which concentration >90% of the strains were inhibited, and MBCs ranging from 0.03 to 0.125 mg/L, at which concentration >90% of the strains were killed.

How long does moxifloxacin stay in your system?

When was Avelox approved for intravenous use?

AVELOX (moxifloxacin hydrochloride) tablets, for oral use AVELOX (moxifloxacin hydrochloride) injection, for intravenous use Initial U.S. Approval: 1999

What are the side effects of Avelox injections?

Commonly seen adverse reactions include tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system effects (hallucinations, anxiety, depression, insomnia, severe headaches, and confusion). These reactions can occur within hours to weeks after starting AVELOX.

How is Avelox used in the treatment of plague?

AVELOX is indicated in adult patients for the treatment of plague, including pneumonic and septicemic plague, due to susceptible isolates of Yersinia pestis and prophylaxis of plague in adult patients. Efficacy studies of moxifloxacin could not be conducted in humans with plague for feasibility reasons.

How long does it take to take Avelox 400 mg?

Patients received AVELOX 400 mg once daily oral, intravenous, or sequentially (intravenous followed by oral). Treatment duration was usually 6 to 10 days, and the mean number of days on therapy was 9 days.

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