What is UniProt blast?
UniProt BLAST Results The left hand panel allows you to filter for Reviewed (UniProtKB/Swiss-Prot), Unreviewed (UniProtKB/TrEMBL) entries, entries with 3D structures or entries from a specific organism. It also allows you to view results by taxonomy, in text and XML formats.
What is UniProt used for?
UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.
Is Swiss-Prot and UniProt same?
UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.
What is Expasy in bioinformatics?
It is an extensible and integrative portal which provides access to over 160 databases and software tools, developed by SIB Groups and supporting a range of life science and clinical research domains, from genomics, proteomics and structural biology, to evolution and phylogeny, systems biology and medical chemistry.
What is UniProt number?
An accession number (AC) is assigned to each sequence upon inclusion into UniProtKB. Accession numbers are stable from release to release. If several UniProtKB entries are merged into one, for reasons of minimizing redundancy, the accession numbers of all relevant entries are kept.
What is ExPASy tool?
Expasy is an online bioinformatics resource operated by the SIB Swiss Institute of Bioinformatics. The individual resources (databases, web-based and downloadable software tools) are hosted in a decentralised way by different groups of the SIB Swiss Institute of Bioinformatics and partner institutions.
Is UniProt a database?
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
How often is UniProt released?
every 8 weeks
UniProt releases are published every 8 weeks (4 weeks until the last 2019 release, 2019_11), with possible exceptions in January and summer due to reduced staff during holidays.
What is Expasy translate tool?
Translate is a tool which allows the translation of a nucleotide (DNA/RNA) sequence to a protein sequence.
What is a good aliphatic index?
The relative volume of a protein occupied by its aliphatic side chains is termed as Aliphatic index (AI). The aliphatic index of cytotoxins in the range of 66.5 to 84.33 indicated that these proteins are thermally stable as well as they contain high amount of hydrophobic amino acids.
What is ExPASy translate tool?
How to search for BLAST sequence similarity in UniProt?
BLAST sequence similarity search against UniProtKB or taxonomic subdivisions, complete proteomes, UniRef, PDB or UniParc – on the UniProt web site.
Are there any BLAST programs available on ExPASy?
BLAST programs available on ExPASy: blastp compares a protein query sequence against a protein sequence database. blastn compares a nucleotide query sequence against a nucleotide sequence database. tblastn compares a protein query sequence against a nucleotide sequence database dynamically translated in all reading frames.
How is blast used to find local alignment?
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.
How is blast used to identify gene families?
BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families [ more… ]. compare an amino acid query sequence against a protein sequence database.