What is ZERBAXA used for?
Ceftolozane/tazobactam is used to treat a variety of bacterial infections. It is a cephalosporin antibiotic. It works by stopping the growth of bacteria.
Is ZERBAXA an antibiotic?
Zerbaxa is an antibiotic used to treat adults with: complicated (difficult to treat) infections of tissues and organs within the belly (intra-abdominal infections); serious kidney infection (acute pyelonephritis);
Is there a generic for ZERBAXA?
Has a generic version of Zerbaxa been approved? No. There is currently no therapeutically equivalent version of Zerbaxa available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Zerbaxa.
What is Ceftolozane tazobactam used for?
The combination of ceftolozane and tazobactam is used to treat certain infections including urinary tract infections and infections of the abdomen (stomach area). It is also used to treat certain types of pneumonia that developed in people who are on ventilators or who were in a hospital.
Does ZERBAXA cover Esbl?
Ceftolozane/tazobactam, a novel cephalosporin in combination with an established beta-lactamase inhibitor, is approved for the treatment of cIAIs and cUTIs caused by ESBL-producing Enterobacteriaceae species, drug-resistant P. aeruginosa, and some Streptococcus species.
Does ZERBAXA cover MRSA?
It also does not cover methicillin-resistant Staphylococcus aureus (MRSA) — although the Cubist rep will tell you they’ve got another drug, Sivextro (also FDA-approved this year) that does that.
How do you give ZERBAXA?
The recommended dosage of ZERBAXA for injection is 1.5 gram (g) (ceftolozane 1 g and tazobactam 0.5 g) for cIAI and cUTI and 3 g (ceftolozane 2 g and tazobactam 1 g) for HABP/VABP administered every 8 hours by intravenous infusion over 1 hour in patients 18 years or older and with a creatinine clearance (CrCl) greater …
Who makes ZERBAXA?
FDA Approves Merck’s ZERBAXA® (ceftolozane and tazobactam) 3g Dose for the Treatment of Adults with Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia (HABP/VABP)
When will ZERBAXA be available?
— Merck is the sole supplier of Zerbaxa and does not have an estimate as to when supply will be available. — The shortage was initially announced in January of 2021 and reverified by Merck on April 12, 2021.
When do you use Recarbrio?
RECARBRIO™ is indicated in patients 18 years of age and older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis, caused by the following susceptible gram-negative microorganisms: Enterobacter cloacae, Escherichia coli.
What is Zerbaxa cost?
The cost for Zerbaxa intravenous powder for injection (1 g-0.5 g) is around $1,317 for a supply of 10 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What generation cephalosporin is Zerbaxa?
Ceftolozane-tazobactam (Zerbaxa) Ceftolozane is a “5th-generation” or “new generation” cephalosporin that is structurally similar to ceftazidime (with a different side chain) and tazobactam is a beta-lactamase inhibitor.
What are the ingredients in the drug Zerbaxa?
ZERBAXA (ceftolozane and tazobactam) is an antibacterial combination product consisting of the cephalosporin antibacterial drug ceftolozane sulfate and the beta-lactamase inhibitor tazobactam sodium for intravenous administration.
What happens if you skip a dose of Zerbaxa?
Skipping doses can increase your risk of infection that is resistant to medication. Zerbaxa will not treat a viral infection such as the flu or a common cold. Store the unmixed Zerbaxa powder in a refrigerator. Protect from light.
How much Ceftolozane is in a Zerbaxa injection?
ZERBAXA 1.5 g (ceftolozane and tazobactam) for injection is a white to yellow sterile powder for reconstitution consisting of ceftolozane 1 g (equivalent to 1.147 g of ceftolozane sulfate) and tazobactam 0.5 g (equivalent to 0.537 g of tazobactam sodium) per vial, packaged in single-dose glass vials.
What’s the best dosage of Zerbaxa to take?
Recommended Dosage. The recommended dosage regimen is ZERBAXA 1.5 gram (g) (ceftolozane 1 g and tazobactam 0.5 g) for injection administered every 8 hours by intravenous infusion over 1 hour in patients 18 years or older and with normal renal function or mild renal impairment.