What is CAH endocrinology?

What is CAH endocrinology?

Congenital adrenal hyperplasia, also called CAH, is a genetic disorder in which the two adrenal glands (located at the top of the kidney) do not function properly because of mutations in the gene for encoding adrenal steroid 21-hydroxylase, which is an enzyme.

What is associated with congenital adrenal hyperplasia?

Congenital adrenal hyperplasia is an inherited condition caused by mutations in genes that code for enzymes involved in making steroid hormones in the adrenal glands. The most common enzyme defect, 21-hydroxylase deficiency, leads to excess amounts of male hormones being produced by the adrenal glands.

Is congenital adrenal hyperplasia an autoimmune disease?

Coexistence of Congenital Adrenal Hyperplasia and Autoimmune Addison’s Disease. Background: Underlying causes of adrenal insufficiency include congenital adrenal hyperplasia (CAH) and autoimmune adrenocortical destruction leading to autoimmune Addison’s disease (AAD).

What is endocrine hyperplasia?

In human disease: Diseases of metabolic-endocrine origin. In general, overproduction results from hyperplasia, an increase in the number of cells (in this case, hormone-secreting cells) in a specific endocrine gland. It can also be caused by neoplasia, the growth of a tumour in an endocrine gland.

Can you grow out of CAH?

You can’t outgrow CAH. People with classical CAH will require treatment for the rest of their lives. Nonclassical CAH patients could be symptomatic or non-symptomatic.

How do you treat congenital adrenal hyperplasia?

Classic CAH is treated with steroids that replace the low hormones.

1. Infants and children usually take a form of cortisol called hydrocortisone.
2. Adults take hydrocortisone, prednisone, or dexamethasone, which also replace cortisol.

Can congenital adrenal hyperplasia go away?

Although there is no cure, with proper treatment, most people who have congenital adrenal hyperplasia can lead normal lives.

Is CAH hereditary?

All forms of congenital adrenal hyperplasia (CAH) are inherited in an autosomal recessive manner. This means that to be affected, a person must have a mutation in both copies of the responsible gene in each cell .

Does congenital adrenal hyperplasia (CAH) have a cure?

Treatment for congenital adrenal hyperplasia depends on the type of CAH you have and how severe your symptoms are. There is no cure for CAH, but many people find symptom relief with medications. Doctors prescribe several types of medications, including salt supplements and steroids, to people living with classic CAH.

What is late-onset adrenal hyperplasia?

Late-onset adrenal hyperplasia refers to a congenital endocrine disorder, associated with an enlargement of the adrenal glands, which causes increased aldosterone production and an insufficiency of cortisol . Late-onset adrenal hyperplasia, or non-classical adrenal hyperplasia (NCAH),…

How does congenital adrenal hyperplasia (CAH) occur?

Congenital adrenal hyperplasia (CAH) is a treatable disorder that occurs when the adrenal glands do not function properly . The result is that normal amoun importantts of hormones are not produced. If left untreated, CAH will cause problems with growth and development and can cause lifethreatening – illness.

What are the symptoms of adrenaline surge?

An adrenaline rush is sometimes described as a boost of energy. Other symptoms include: rapid heart rate. sweating. heightened senses. rapid breathing. decreased ability to feel pain. increased strength and performance.