What is theobroma oil used for?
Cocoa butter, also called theobroma oil, is a pale-yellow, edible fat extracted from the cocoa bean. It is used to make chocolate, as well as some ointments, toiletries, and pharmaceuticals.
What is source of theobroma oil?
Theobroma oil is extracted from roasted cacao beans (Theobroma cacao). It primarily contains glycerides of stearic, palmitic, oleic, arachidic, and linoleic acids. Theobroma oil is used in the manufacture of chocolates and soaps.
What are the disadvantages of theobroma oil?
However, the most prominent disadvantage of theobroma oil is its polymorphism. Theobroma oil makes an ideal melting suppository base due to a melting point near human body temperature. In this state, theobroma oil is in its β-crystalline form.
What is the role of theobroma oil in suppositories?
Cocoa butter or theobroma oil is used as a suppository base mainly because, in large measure, it accomplishes the requirements of an ideal base. Thus, the finished suppository would not be usable as it melts at room temperature.
Which of following is substitute for theobroma oil?
As a substitute of theobroma oil a number of hydrogenated oils, e.g. hydrogenated edible oil, arachis oil, coconut oil, palm kernel oil, stearic and a mixture of oleic and stearic acids are recommended.
Which is the stable form of theobroma oil?
Theobroma oil, heated to about 60°C and cooled rapidly, will crystallize in an alpha configuration characterized by a melting point below 30°C. The alpha form is metastable and will slowly revert to the beta form, with the characteristic melting point approaching 35°C.
Which of following is substitute for Theobroma oil?
Which polymer of Theobroma oil is most stable?
This indicates that PKO blend possesses better thermal stability.
Why are suppository used?
Why Use Them You might need a suppository if: The drug you’re taking would break down too quickly in your digestive tract if you took it as a pill or liquid. You can’t swallow medicine. You’re vomiting and can’t keep a pill or liquid down.
What is evaluation of suppositories?
Suppositories were evaluated for physical appearance, uniformity of weight, disintegration time, drug content, in-vitro dissolution study, in-vitro diffusion study, in-vivo study and stability studies.
What is melting point of theobroma oil?
For the character and tests for purity of oil of theobroma, see the pharmacopoeias. Its melting point (31–34°) makes it ideal for the preparation of suppositories.
What is suppository form?
A suppository is a dosage form used to deliver medications by insertion into a body orifice where it dissolves or melts to exert local or systemic effects.