What is a microfluidic chamber?
In general, microfluidic devices are designed to contain or deliver sub-milliliter volumes of fluid, including chemicals and biological samples. Microfluidic device chambers from Grace Bio-Lab Chambers most frequently are: FlexWell™ Incubation Chambers. CoverWell™ Perfusion Chambers.
What is a microfluidic reactor?
Microfluidic reactors exhibit intrinsic advantages of reduced chemical consumption, safety, high surface-area-to-volume ratios, and improved control over mass and heat transfer superior to the macroscopic reaction setting.
What is microfluidic system?
Microfluidics is the science and technology of systems that process or manipulate small amounts of fluidics (10−9 to 10−18L), using channels measuring from tens to hundreds of micrometers. From: Chemical Analysis of Food: Techniques and Applications, 2012.
How do microfluidic chambers work?
The microfluidic chamber consists of a molded elastomeric polymer placed on a glass coverslip (Fig. 1A). A physical barrier with embedded microgrooves connects the somal and axonal compartments. Microgrooves that connect the compartments allow the passage of neurites to the axonal compartment, but not of cell bodies.
What is microfluidic technique?
Definition of microfluidics. Microfluidics is both the science which studies the behaviour of fluids through micro-channels, and the technology of manufacturing microminiaturized devices containing chambers and tunnels through which fluids flow or are confined.
Why is PDMS used in microfluidic devices?
PDMS, as an elastomer, is known for its mold-release properties and ability to replicate features down to the nanoscale, with low shrinkage during cure (around 1%) and excellent elastic properties.
What is microfluidic drug delivery system?
Microfluidic drug delivery systems. Drug delivery systems aim at the controlled release and targeted delivery of pharmaceutical compounds to the body. These engineered technologies increase the effectiveness of drugs by targeting the infected organ.
What is PDMS microfluidic device?
Introduction to polydimethylsiloxane Polydimethylsiloxane, called PDMS or dimethicone, is a polymer widely used for the fabrication and prototyping of microfluidic chips. Apart from microfluidics, it is used as a food additive (E900), in shampoos, and as an anti-foaming agent in beverages or in lubricating oils.
What can be done with a microfluidics interaction chamber?
Used for emulsions (water in oil), cell disruption, deagglomeration, particle size reduction, and dispersions. Microfluidics Z type chambers are available with a microchannel range of 87 to 1100 μm with varying shear rates optimized for each application.
What can be mixed in a microliter chamber?
High turbulence inside the microliter volumes is also responsible for mixing on the nano scale. Used for emulsions (oil in water), liposomes, and polymer encapsulations. Microfluidics Y type chambers are available with a microchannel range of 75 to 125 μm with varying shear rates optimized for each application.
Why does a Microfluidizer have a high shear field?
In addition to the high shear forces, impact forces from collisions with the micro channel walls and with the fluid itself are the other primary forces that assist in particle/globule size reduction. A change of velocity in magnitude or direction exposes the fluid to a high shear field.
What is the role of the APM in a Microfluidizer?
The role of the auxiliary processing module (APM) is to act as premixing or pre-processing module that is located upstream of the smaller geometry of the Z-type IXC. The auxiliary processing module (APM) also stabilizes the fluid flow by acting as an intermediate pressure relief between the high pressure IXC and the atmosphere.