How does bisphenol A or BPA cause its endocrine disruptor effects?
Generally, BPA acts on hormonal level by distorting hormonal balance and inducing estrogenic effects through binding with estrogen-related receptors (ERR) [20]. The resultant effects are numerous of which hormonal related abnormalities have been mostly reported.
How does BPA affect behavior?
BPA exposure in childhood was associated with higher levels of anxiety, depression, hyperactivity, inattention, and conduct problems. Limited observational evidence suggests an association between both prenatal and childhood exposure to BPA and adverse behavioral outcomes in children.
How does BPA affect the female reproductive system?
BPA can affect the hypothalamic system. The hypothalamic-pituitary-ovarian axis controls the ability of the mammalian female to ovulate and to prepare the reproductive organs to support potential pregnancy. BPA exposure resulted in the decrease of the reproductive capacity and delay or elimination of puberty [1].
What system does BPA affect?
Research in humans has linked even low dose BPA exposure to cardiovascular problems, including coronary artery heart disease, angina, heart attack, hypertension, and peripheral artery disease.
How does BPA affect child development?
(10, 11) Since BPA has endocrinologic activity, there is concern that BPA may act on hormonally mediated pathways to disrupt normal growth and development. Prenatal and childhood exposure to BPA may be associated with altered neurodevelopment, obesity, and precocious puberty.
Is BPA bad for pregnancy?
New research suggests that prenatal exposure to bisphenol A, or BPA, may cause your child to develop health issues, like diabetes and heart disease, later in life. BPA is an hormone-disrupting chemical used to manufacture plastics, such as plastic bottles, metal cans, and even cash register receipts.
Is bisphenol A neurotoxin?
Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons.
How does bisphenol an affect health?
Bisphenol A is found in the hard plastic bottles many people use every day. BPA is an endocrine disruptor. It can imitate the body’s hormones, and it can interfere with the production, secretion, transport, action, function, and elimination of natural hormones. BPA can behave in a similar way to estrogen and other hormones in the human body.
What are the harmful effects of bisphenol?
Hazards Reproductive disorders. In 2013, scientists from Brigham and Women’s Hospital published findings showing that BPA exposure can affect egg maturation in humans. Heart disease. Type 2 diabetes and body weight. Fetal brain development. Breast and prostate cancer. Asthma.
How is bisphenol A harmful to our health?
BPA is present all around us in the environment and in manufactured products.
What are the risks of bisphenol A (BPA)?
Fast facts on bisphenol A, or BPA BPA is present all around us in the environment and in manufactured products. Research has linked exposure to fertility problems, male impotence, heart disease and other conditions. Some reports say that current levels of BPA are low and not a danger to humans.