What is a verrucous?
The term “verrucous” has been applied for lesions showing a keratotic exophytic surface composed of sharp or blunt epithelial projections with keratin-filled invaginations (plugging), but without obvious fibrovascular cores.
What is Ackerman tumor?
Verrucous carcinoma, also known as Ackerman tumor, is a slow-growing variant of squamous cell carcinoma. Involvement of the esophagus is relatively rare. More often, this tumor involves the upper airway, genitalia, endometrium, anus, or feet.
What is the meaning of verrucous carcinoma?
Verrucous carcinoma (VC) is defined as a warty variant of SCC characterized by a predominantly exophytic overgrowth of well-differentiated keratinizing epithelium with locally aggressive pushing margins.
Why is verrucous carcinoma called carcinoma?
In spite of being called a ‘carcinoma’, the strict definition of VC is that these tumors lack dysplastic cytologic features, and that there is no invasion by the tumor cells through the basement membrane.
What does Verruciform mean?
wart
[ və-rōō′sə-fôrm′ ] adj. Resembling or shaped like a wart.
What is Verruciform Xanthoma?
Verruciform xanthoma is a rare benign proliferative lesion of the oral cavity, characterized by the presence of foam cells within the connective tissue papillae. Foam cells are macrophages with lipid content, thought to be derived from the keratinocytes.
What is Buschke Lowenstein tumor?
Buschke-Lowenstein tumor (BLT) is a solid tumor that usually develops around the external genitals or anus. BLT grows slowly into a bulky, cauliflower-shaped mass. It often spreads into surrounding tissues and causes damage.
How is verrucous carcinoma diagnosed?
A skin biopsy is always required for definitive diagnosis of verrucous carcinoma, despite the fact that the diagnosis is suspected strongly on clinical grounds. Biopsy is performed routinely in the physician’s office using a local anesthetic.
How can you tell the difference between verrucous and verrucous carcinoma?
Oral verrucous hyperplasia (OVH) may be a precursor lesion of oral verrucous carcinoma (OVC) and it resembles oral VC both clinically and histopathologically. [1] OVC is a rare variant of oral squamous cell carcinoma (OSCC), first described by Ackermann, and henceforth also known as Ackermann’s tumor.
Can Verrucous carcinoma be cured?
Verrucous carcinoma usually is cured with appropriate therapy. However, recurrence of cutaneous carcinoma with clear surgical margins has been reported.
What is Verruciform keratosis?
Microscopically, verrucal keratosis shows a heavily keratinized surface. The presence of abundant keratohyalin granules in the stratum granulosum is characteristic and helps differentiate the lesion from verrucous carcinoma which characteristically demonstrates no granules, or few.
What is giant condyloma acuminata?
Giant condylomata acuminata of Bushke-Löwenstein (GCBL) is a rare, slow-growing verrucous tumor of the penis and anogenital region which can grow up to twenty centimeters in size and can locally destroy contiguous structures.
What kind of cancer is verrucous squamous cell carcinoma?
Verrucous Squamous Cell Carcinoma of Skin is a malignant tumor of skin that typically affects elderly men and women. It has a lower metastatic potential than conventional squamous cell carcinomas. The verrucous form is a rare subtype of squamous cell carcinoma (SCC) with a slower growth.
Is it possible for oral verrucous carcinoma to recur?
Local recurrence is not uncommon, but metastasis to distant parts of the body is rare. Patients with oral verrucous carcinoma may be at greater risk of a second oral squamous cell carcinoma, for which the prognosis is worse.
When was verrucous carcinoma of the oral cavity defined?
Verrucous carcinoma (VC) was defined by Ackerman in 1948 [ 1. L. V. Ackerman, “Verrucous carcinoma of the oral cavity,” Surgery, vol. 23, no. 4, pp. 670–678, 1948. View at: Google Scholar. See in References. ] as a diagnostically problematic squamous cell neoplasia involving lip, oropharyngeal, and laryngeal mucosa.
What kind of cysts are found in verruciform?
Verruciform and Condyloma-like Squamous Proliferations in the Anogenital Region Histologically, besides the hallmark of a superficial plate-like epithelial proliferation, some variations are occasionally reported: the presence of randomly scattered keratin-filled cysts]