What does Rhinocerebral mean?
Rhinocerebral (sinus and brain) mucormycosis is an infection in the sinuses that can spread to the brain. This is most common in people with uncontrolled diabetes and in people who have had a kidney transplant.
What is Rhinocerebral Zygomycosis?
Rhinocerebral mucormycosis, also called zygomycosis, is a rare disease caused by filamentous fungi involving the nose, paranasal sinuses, and brain. It is an opportunistic pathogen commonly found in immunocompromised individuals.
Is Rhinocerebral mucormycosis curable?
To have a case of rhinocerebral mucormycosis with intracranial involvement cured by medical therapy alone is indeed rare and fascinating. Fortunately, in this case, the diagnosis was made early enough for treatment with amphotericin B lipid complex to be effective.
How do you get Rhinocerebral Zygomycosis?
Risk factors for rhinocerebral mucormycosis include the following:
- Diabetes mellitus.
- Iron overload.
- Burns.
- Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)
- Blood dyscrasias.
- Transplantation.
- Immunosuppression (ie, prednisone therapy)
- Chemotherapy.
What is a mucormycosis?
Mucormycosis (previously called zygomycosis) is a serious but rare fungal infection caused by a group of molds called mucormycetes. These molds live throughout the environment. Mucormycosis mainly affects people who have health problems or take medicines that lower the body’s ability to fight germs and sickness.
What is pulmonary mucormycosis?
Pulmonary mucormycosis (PM) is an uncommon fungal infection most often seen in immunocompromised patients. The fungus grows on decaying food, soil, and animal excrement. Patients usually become infected by inhalation of spores.
Why do you get mucormycosis after Covid?
During the second wave of the COVID-19 pandemic in India, an unprecedented surge in cases of mucormycosis was observed: immune dysregulation caused by the SARS-CoV-2 and the use of broad-spectrum antibiotics and corticosteroids—particularly in patients with poorly controlled diabetes with ketoacidosis—is likely to have …
Why mucormycosis is called Zygomycosis?
What are the symptoms of Rhinocerebral mucormycosis?
Symptoms of rhinocerebral (sinus and brain) mucormycosis include:
- One-sided facial swelling.
- Headache.
- Nasal or sinus congestion.
- Black lesions on nasal bridge or upper inside of mouth that quickly become more severe.
- Fever.
How do you treat rhizopus?
The accepted standard for treatment of zygomycetes is amphotericin B and surgical debridement, however recent data suggest that combined treatment modalities may be optimal. Newer anti-fungal agents show success in vitro and in animal models.
Is mucormycosis serious?
Why is there mucormycosis after COVID-19?
How does rhinocerebral mucormycosis affect the human body?
Rhinocerebral mucormycosis is a rare opportunistic infection of the sinuses, nasal passages, oral cavity, and brain caused by saprophytic fungi. The infection can rapidly result in death. Rhinocerebral mucormycosis commonly affects individuals with diabetes and those in immunocompromised states.
What is the survival rate for mucormycosis without cerebral involvement?
(Amphotericin became available in the 1950s.) Mucormycosis has a fulminantly fatal clinical pattern. The survival rates among patients with invasive sinus disease without cerebral involvement may be as high as 50-80%. If infection spreads to the brain, the case fatality rate can exceed 80%.
Can a mucormycosis infection spread to the lungs?
Types of mucormycosis. Mucormycosis can affect nearly any part of the body, but it most commonly affects the sinuses or the lungs in people who have weakened immune systems. Rhinocerebral (sinus and brain) mucormycosis is an infection in the sinuses that can spread to the brain.
What kind of fungal infection is called mucormycosis?
Mucormycosis (sometimes called zygomycosis) is a serious but rare fungal infection caused by a group of molds called mucormycetes.