What is monoclonal spike?
A monoclonal spike (M spike or paraprotein) on serum protein electrophoresis (SPEP) is a frequent finding in the general population and typically is pathognomonic of an asymptomatic, premalignant condition called monoclonal gammopathy of undetermined significance (MGUS).
What is an M protein spike?
○ The malignant plasma cells secrete an antibody, or. immunoglobulin, called the M- protein, or M- spike, or paraprotein or myeloma protein. It can be detected in the blood and/or the urine of most myeloma patients.
What is the ICD 10 code for monoclonal gammopathy?
D47.2
D47. 2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
What is a restricted band M spike?
-A characteristic monoclonal band (M-spike) is often found on serum protein electrophoresis (SPE) in the gamma globulin region and, more rarely, in the beta or alpha-2 regions. The finding of an M-spike, restricted migration, or hypogammaglobulinemic SPE pattern is suggestive of a possible monoclonal protein.
What is considered a high M spike?
Patients with a higher M spike (greater than 1.5 g/dL) or abnormal SFLC ratio are at a higher risk of disease progression. In addition, patients with IgM or IgA MGUS have a higher rate of developing myeloma than patients with IgG MGUS.
What is M Guss?
MGUS, short for monoclonal gammopathy of undetermined significance, is a condition that causes the body to create an abnormal protein. This protein is called monoclonal protein, or M protein. It’s made by white blood cells called plasma cells in the body’s bone marrow.
What is the ICD-10 code for monoclonal gammopathy of undetermined significance?
The ICD code D472 is used to code Monoclonal gammopathy of undetermined significance.
Can M spike fluctuate?
The M-spike usually remains stable with small fluctuations in its concentration, until MM develops. Patients are at higher risk for developing venous thromboembolism, osteoporosis, and fractures, even in the absence of progression to MM.
What are the symptoms of monoclonal gammopathy ICD 9?
Monoclonal gammopathy is a disorder where there is abnormal protein (monoclonal protein) in the blood. Symptoms include anemia, weakness, bleeding, increased bruising, pain in the bones, fatigue, and low red blood cells count. Filed Under: ICD 9 Codes Tagged With: Endocrine and Metabolic ICD 9 Codes.
When to use ICD-9 CM 273.1 monoclonal paraproteinemia?
Monoclonal paraproteinemia Short description: Monoclon paraproteinemia. ICD-9-CM 273.1 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 273.1 should only be used for claims with a date of service on or before September 30, 2015. You are viewing the 2012 version of ICD-9-CM 273.1.
What do you mean by monoclonal gammopathy of undetermined significance?
Monoclonal gammopathy of undetermined significance (MGUS) Print. Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an abnormal protein — known as monoclonal protein or M protein — is in your blood. The protein is produced in a type of white blood cell (plasma cells) in your bone marrow.
Can a serum monoclonal spike be pathognomonic?
Abstract. A monoclonal spike (M spike or paraprotein) on serum protein electrophoresis (SPEP) is a frequent finding in the general population and typically is pathognomonic of an asymptomatic, premalignant condition called monoclonal gammopathy of undetermined significance (MGUS). MGUS occurs in around 3% of people older than 50…