What is the treatment for parathyroid?
Treatment options for the parathyroid disease include monitoring, medication, dietary supplements, and surgery. Surgery is the most effective option to treat the disease. It involves removing overactive parathyroid glands and can be performed either in a minimally invasive way or by a standard neck exploration.
How is cinacalcet administered?
The recommended starting oral dose of Sensipar is 30 mg twice daily. The dose of Sensipar should be titrated every 2 to 4 weeks through sequential doses of 30 mg twice daily, 60 mg twice daily, and 90 mg twice daily, and 90 mg 3 or 4 times daily as necessary to normalize serum calcium levels.
Why is cinacalcet prescribed?
CINACALCET (sin a CAL set) is used to treat patients with chronic kidney disease who are on dialysis. It is also used to treat high levels of calcium in the blood of patients with certain parathyroid gland problems.
What is the cost of cinacalcet?
The cost for cinacalcet oral tablet 30 mg is around $335 for a supply of 30, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What type of doctor treats parathyroid disease?
Within the endocrine surgery community, a surgeon who performs 50 or more parathyroid operations per year is considered an expert parathyroid surgeon. These surgeons can be found through the American Association of Endocrine Surgeons (AAES).
How does cinacalcet work for patients with PHPT?
Cinacalcet may be considered to reduce serum calcium and parathyroid hormone serum levels in patients with pHPT who cannot undergo surgery or are unwilling to do so and those with refractory pHPT after parathyroidectomy. As the effects of cinacalcet on bone mineral density are uncertain, and bone biopsies are rarely available]
How does cinacalcet help with hypophosphatemia and hypercalcemia?
Cinacalcet almost always controls hypercalcemia and hypophosphatemia sufficiently. PTH levels are lowered, and cognitive parameters improve. While an increase in bone mineral density DEXA scan scores was not demonstrated in cinacalcet trials, the same applies to more than half of patients after parathyroidectomy.
Which is the best treatment for primary hyperparathyroidism?
Abstract Although parathyroidectomy remains the only curative approach to most primary hyperparathyroidism cases, medical treatment with cinacalcet HCl has been proven to be a reasonable alternative for several patient subgroups. Cinacalcet almost always controls hypercalcemia and hypophosphatemia sufficiently.
Is there a risk of nephrolithiasis with cinacalcet?
Nephrolithiasis was not found to occur more frequently in cinacalcet trial groups, but urine calcium excretion as one major risk factor of this complication of primary HPT may increase on cinacalcet.