What is fosfomycin monurol used for?
Fosfomycin is used to treat urinary tract infection and cystitis (bladder infection) in women. This medicine is an antibiotic. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
Is monurol the same as fosfomycin?
MONUROL Granules for Oral Solution is available as a single-dose sachet containing the equivalent of 3 grams of fosfomycin.
What bacteria does monurol treat?
Fosfomycin (Monurol) targets bacteria in the bladder such as Escherichia coli and Enterococcus faecalis. These bacteria are most common for causing the symptoms associated with UTI.
How many times can you take monurol?
Do not take this medicine in larger or smaller amounts or for longer than recommended. Monurol is usually given in only one dose. Do not take more than a single dose unless your doctor tells you to. You may take Monurol with or without food.
How quickly does monurol work?
It is important that this medication be taken exactly as prescribed by your doctor. You should notice improvement in your symptoms within 2 to 3 days. If your symptoms do not improve by the fourth day, you should contact your doctor.
Does monurol work immediately?
I love Monurol medication because it is a one stop shop for a painful UTI. You pour the orange-flavored granules into 4 oz of room-temp water. You’re UTI will start to go away within approximately 45 minutes.
What is the maximum concentration of fosfomycin after taking Monurol?
After a single 3-gram dose of MONUROL, the mean (± 1 SD) maximum serum concentration (C max) achieved was 26.1 (± 9.1) mcg/mL within 2 hours. The oral bioavailability of fosfomycin is reduced to 30% under fed conditions.
What is the concentration of fosfomycin in urine?
A mean urine fosfomycin concentration of 706 (± 466) μg/mL was attained within 2-4 hours after a single oral 3-gm dose of MONUROL under fasting conditions. The mean urinary concentration of fosfomycin. was 10 μg/mL in samples collected 72-84 hours following a single oral dose of MONUROL.
How is the bioavailability of fosfomycin reduced under fed conditions?
The oral bioavailability of fosfomycin is reduced to 30% under fed conditions. Following a single 3-gm oral dose of MONUROL with a high-fat meal, the mean Cmax achieved was 17.6 (± 4.4) μg/mL within 4 hours. Cimetidine does not affect the pharmacokinetics of fosfomycin when coadministered with MONUROL.
Can you take Fosfomycin Trometamol 3 g in urine?
A single oral dose of fosfomycin trometamol 3 g (the approved dosage) achieves high concentrations in urine.