What schedule drug is atropine?
Controlled Substance: Diphenoxylate HCl and atropine sulfate tablets are classified as a Schedule V controlled substance by federal regulation.
What type of drug is atropine where and how does it act to block the action of acetylcholine?
Atropine is commonly classified as an anticholinergic or antiparasympathetic (parasympatholytic) drug. More precisely, however, it is termed an antimuscarinic agent since it antagonizes the muscarine-like actions of acetylcholine and other choline esters.
What is the action of atropine sulfate?
Mechanism of action. The most important therapeutic action of atropine is the inhibition of smooth muscle and glands innervated by postganglionic cholinergic nerves. It also has central nervous system activity, which may be stimulating or depressing depending upon the dose.
What is the pharmacokinetics of atropine?
Pharmacokinetics: Atropine is rapidly and well absorbed after intramuscular administration. Atropine disappears rapidly from the blood and is distributed throughout the various body tissues and fluids.
Why is lomotil a schedule 5?
Lomotil is a Schedule V controlled substance, which means it has a medical use but may be misused. It contain small quantities of narcotics (powerful pain relievers also called opioids). Diphenoxylate, one of the ingredients in Lomotil, is itself a Schedule II controlled substance.
When should atropine be administered?
Atropine is the first-line therapy (Class IIa) for symptomatic bradycardia in the absence of reversible causes. Treatments for bradydysrhythmias are indicated when there is a structural disease of the infra-nodal system or if the heart rate is less than 50 beats/min with unstable vital signs.
What are the therapeutic actions for atropine?
Pharmacodynamics. Atropine reduces secretions in the mouth and respiratory passages, relieves the constriction and spasm of the respiratory passages, and may reduce the paralysis of respiration that results from toxic nerve agents which increase anticholinesterase activity in the central nervous system.
What action of atropine causes the dilation effect?
This medicine works by blocking the chemical acetylcholine, which relaxes the ciliary muscle of the eye and causes the pupil to dilate.
What is the role of atropine?
Atropine is a prescription medicine used to treat the symptoms of low heart rate (bradycardia), reduce salivation and bronchial secretions before surgery or as an antidote for overdose of cholinergic drugs or mushroom poisoning.
How is atropine administered?
Atropine is administered by intravenous injection or intramuscular injection. Other pharmaceutical forms/strengths may be more appropriate in the cases where a dose above 0.5 mg is required. All these contra-indications are however not relevant in life-threatening emergencies (such as bradyarrhythmia, poisoning).
What is atropine like action?
What is a Schedule V drug?
Schedule V drugs, substances, or chemicals are defined as drugs with lower potential for abuse than Schedule IV and consist of preparations containing limited quantities of certain narcotics. Schedule V drugs are generally used for antidiarrheal, antitussive, and analgesic purposes.
What is the duration of action of atropine?
Part of atropine administered in the form of ophthalmic solution is likely to diffuse into the general circulation. It crosses the placental barrier and traces can be found in various secretions, of which breast milk. The duration of action of atropine administered by general route would be of approximately six hours.
Is atropine anticholinergic?
Atropine is an anticholinergic medication that may be administered in a variety of medical situations. Anticholinergic drugs block the action of acetylcholine , a neurotransmitter found in many places throughout the body. Atropine is often used during surgical procedures performed under general anesthesia.
What is atropine classified as?
Atropine is commonly classified as an anticholinergic or antiparasympathetic (parasympatholytic) drug. More precisely, however, it is termed an antimuscarinic agent since it antagonizes the muscarine-like actions of acetyl-choline and other choline esters.