Where does clear cell renal cancer spread?

Where does clear cell renal cancer spread?

The most common sites are the lungs (76%), local lymph nodes (66%), bone (42%), and liver (41%); approximately 15% of patients demonstrate head and neck metastases, while only 1% experience head and neck metastases in the absence of other sites.

What is the survival rate of clear cell renal cell carcinoma?

The 5-year survival rate for patients with ccRCC is 50-69%. When ccRCC is already large or has spread to other parts of the body, treatment is more difficult and the 5-year survival rate is about 10%.

How fast does clear cell renal cancer grow?

The average tumor growth rate was 0.80 (range, 0.16-3.80) cm/year. Clear cell carcinoma (0.86 cm/year) tended to grow faster than papillary cell carcinoma (0.28 cm/year) (P = 0.066).

Is clear cell cancer hereditary?

Four hereditary renal cell cancer syndromes and the genes that cause them have been identified. VHL is a hereditary syndrome that increases the risk of renal cell cancer and renal cysts. VHL is associated with a clear-cell type renal cell cancer, which is typically slow growing.

What causes clear cell carcinoma kidney?

Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.

What causes clear cell renal carcinoma?

What is metastatic clear cell renal cell carcinoma?

Metastatic clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer. Localized ccRCC has a favorable surgical outcome. However, one third of ccRCC patients will develop metastases to the lung, which is related to a very poor outcome for patients.

Survival for renal cell carcinoma. Patients with regional lymph node involvement or extracapsular extension have a survival rate of 12-25%. Although renal vein involvement does not have a markedly negative effect on prognosis, the 5-year survival rate for patients with stage IIIB renal cell carcinoma is 18%.

What are the warning signs of renal cell carcinoma?

7 Symptoms of Renal Cell Carcinoma Hematuria. Lower back pain. Lump. Anemia. Fatigue. Fever. Weight loss.

How deadly is renal cell carcinoma?

Renal Cell Carcinoma ( RCC ), which represents 2% of all adult cancers, is the most lethal of common urologic cancers, with approximately 35% of patients dying from the disease at the five-year mark.

What is renal cell carcinoma and how is it treated?

In addition to overall health and age at diagnosis, treatment for kidney cancer depends largely on the stage and spread of the disease. A person can function with just one kidney, so early-stage RCC is often treated with surgery that removes a portion or the entire affected kidney.