What is the function of UniProt?
UniProt is the central resource for storing and interconnecting information from large and disparate sources, and the most comprehensive catalog of protein sequence and functional annotation.
What does UniProt stand for?
Universal Protein Resource
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data.
Is Swiss-Prot and UniProt same?
UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.
What are the features of UniProt?
THE UNIPROT KNOWLEDGEBASE (UNIPROT)
- High-quality annotation.
- Manual annotation by curators based on literature and sequence analysis.
- Automatic classification and annotation.
- High-quality Automated and Manual Annotation of microbial Proteomes (HAMAP)
- Standardized nomenclature and controlled vocabularies.
What can be find using UniProt?
UniProt
- Annotation score.
- Function.
- Subcellular location.
- Pathology and Biotech.
- PTM / processing.
- Interaction.
- Expression.
- Family and domains.
Where is UniProt located?
Geneva, Switzerland
The UniProt consortium SIB, located in Geneva, Switzerland, maintains the ExPASy (Expert Protein Analysis System) servers that are a central resource for proteomics tools and databases.
What type of knowledge database is UniProt?
protein sequence database
UniProtKB/Swiss-Prot (reviewed) is a high quality manually annotated and non-redundant protein sequence database, which brings together experimental results, computed features and scientific conclusions.
How often is UniProt released?
every 8 weeks
UniProt releases are published every 8 weeks (4 weeks until the last 2019 release, 2019_11), with possible exceptions in January and summer due to reduced staff during holidays.
How many sequences are in UniProt?
INTRODUCTION Release 2021_03 of 02-Jun-2021 of UniProtKB/TrEMBL contains 219174961 sequence entries, comprising 75271144009 amino acids. 14881314 sequences have been added since release 2021_02, the sequence data of 85669 existing entries has been updated and the annotations of 83429017 entries have been revised.
What is UniProt sequence?
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
What is the purpose of the UniProt project?
The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.
How is the annotation score used in UniProtKB?
The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score cannot be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein. More…
Where do you store an official gene name?
If an official gene name is provided by nomenclature committees, we usually store it in the ‘Name’ token with the recommended casing. However, there are some exceptions to this rule: a) Many species have no established nomenclature committee.