What causes gingival fibromatosis?
The condition may be related to hereditary factors and occurs as a non-syndromic hereditary gingival fibromatosis (HGF) or as a part of a syndrome. It may also develop in susceptible individuals as a side effect of systemic medications, including the anti-seizure, immunosuppressant, or calcium channel blockers.
Is gingival hypertrophy reversible?
Gingival hyperplasia can be resolved by improving oral hygiene habits. In more severe cases, surgical treatment is necessary.
How does phenytoin cause gingival hyperplasia?
Phenytoin has been shown to induce gingival overgrowth by its interaction with a subpopulation of sensitive fibroblasts. Cyclosporine has been suggested to affect the metabolic function of fibroblast (eg, collagen synthesis, breakdown).
What is hypertrophy of gums?
Gingival (Gum) enlargement, also known as gingival hyperplasia or hypertrophy, is an abnormal overgrowth of gingival tissues.
How is gingival fibromatosis treated?
HGF does not resolve spontaneously and the treatment of choice is gingivectomy, which can be performed with an internal or external bevel incision (2,5). Performing surgery after eruption of the permanent teeth reduces the rate of recurrence (2).
How rare is gingival fibromatosis?
Gingival fibromatosis (GF) is a rare disease that is characterized by benign, slowly progressive, non-hemorrhagic, fibrous enlargement of maxillary and mandibular gingival. The prevalence is one per 175 000 population, and men and women are equally affected.
How long does it take for gingival hyperplasia to go away?
How long does it take for gingival hyperplasia to go away? After you stop taking the medication(s) that caused gingival hyperplasia or start treatment for the condition, it takes one to eight weeks for the lesions to disappear.
What is the difference between gingival hyperplasia and hypertrophy?
While hyperplasia refers to an increased number of cells, hypertrophy refers to an increase in the overall size of the individual cells. These identifications cannot be performed with a clinical examination and evaluation of the tissue, the term gingival enlargement is a more accurate description.
Is gingival hyperplasia normal with phenytoin?
Gingival enlargement is a well-recognized adverse effect and occurs in about 50% of patients receiving phenytoin. [12] As per evidence, drug-induced gingival enlargement may improve by substitution with other anticonvulsant drugs, along with reinforcement of good oral hygiene regimen.
Which drugs cause gingival hyperplasia?
Drug-induced gingival overgrowth is a side effect associated principally with 3 types of drugs: anticonvulsant (phenytoin), immunosuppressant (cyclosporine A), and various calcium channel blockers (nifedipine, verapamil, diltiazem).
What drug causes gum hypertrophy?
Drugs like PHT, phenobarbitone, and primidone are metabolized to 5-(4-hydroxyphenyl) 5-phenyl hydantoin (4-HPPH), responsible for overgrowth gingival tissue. At times, multiple anticonvulsants are given together, acting synergistically and aggravating the condition.
What is gingival fibromatosis?
Hereditary gingival fibromatosis (HGF) is a rare disorder characterized by a benign, non-hemorrhagic, fibrous gingival overgrowth that can appear in isolation or as part of a syndrome. Clinically, a pink gingiva with marked stippling can be seen to cover almost all the tooth, in many cases preventing eruption.
Where does a gingival cyst occur in an adult?
Gingival cyst of the adult. Gingival cyst is a benign odontogenic cyst that occurs primarily in middle aged adults. There is a gingival cyst of a newborn that is basically the same lesion but occurs in a different area and obviously on a different age group. The cyst most commonly occurs in the mandible in the canine and premolar areas and…
Is there any treatment for a gingival cyst?
No treatment of any kind was done, except for parental counseling and reassurance. It is important to note that management of all oral inclusion cysts (dental lamina cysts, Epstein pearls and Bohn’s nodules) remains the same, as all these have a self-limiting nature and require no treatment. Figure 3.
How big is a gingival cyst in a newborn?
Gingival cysts of the newborn also called Bohn’s nodules, can manifest as few or many, white to yellowish, round to oval, nodes in the maxillary and/or mandibular gingiva and alveolar ridge of newborns 1). These nodes generally measure 2 to 3 millimeters in their largest dimension.
Can a cyst grow in the back of the mandible?
Keratocystic Odontogenic Tumors are cysts that grow in the back of the lower jaw or mandible and have similar characteristics to other cysts. You can get a diagnosis for it with a biopsy and microscopic analysis, as well as a panoramic x-ray. Swelling is frequently the sole symptom that a patient will have.