What is the drug gemfibrozil used for?
Gemfibrozil is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and triglycerides (other fatty substances) in the blood in certain people with very high triglycerides who are at risk of pancreatic disease (conditions affecting the pancreas, a gland that produces …
What is the side effects of gemfibrozil?
The more common side effects that can occur with use of gemfibrozil include:
- stomach upset.
- stomach pain.
- nausea.
- vomiting.
- diarrhea.
- constipation.
- rash.
- dizziness.
What class of drugs is gemfibrozil?
Valeric acid
Gemfibrozil/Classification
What is the action of gemfibrozil?
The mechanism of action of gemfibrozil is not entirely understood. It increases VLDL clearance by stimulating vascular endothelial cell lipoprotein lipase activity. Gemfibrozil binds to PPAR-alpha which, in turn, increases fatty acid oxidation and reduces triglycerides levels.
How can I lower my triglycerides at home?
Exercise. Physical activity: The American Heart Association (AHA) recommends a weekly minimum of 40 minutes of moderate intensity aerobic exercise, 3 to 4 times every week. Weight. Because extra calories are converted to triglycerides and stored as fat, if you reduce your calories, you will reduce triglycerides.
Why do you have to take gemfibrozil 30 minutes before meals?
Take your doses ½-1 hour before a meal. This is because gemfibrozil is absorbed better when your stomach is empty. It is best to take gemfibrozil with the same meals each day, as this helps remind you to take your doses regularly. The ideal times to take your doses are before your breakfast and evening meal.
Is gemfibrozil bad for your liver?
Gemfibrozil is a fibric acid derivative used in the therapy of hypertriglyceridemia and dyslipidemia. Gemfibrozil therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury.
Can I take gemfibrozil after I eat?