What is mTeSR?
Product Description. mTeSR™1 medium is a complete, serum-free, defined formulation designed for the feeder-free maintenance and expansion of human embryonic stem (ES) cells1,2 and human induced pluripotent stem (iPS) cells3-5 in the undifferentiated state.
What is in mTeSR plus?
mTeSR™ Plus is a stabilized, serum-free cell culture medium for the feeder-free maintenance and expansion of human embryonic stem (ES) and induced pluripotent stem (iPS) cells. It is based on the mTeSR™1 formulation1, 2, the most widely published feeder-free cell culture medium for human ES and iPS cells.
What does Feeder-free mean?
A feeder-free culture system is designed to keep the stem cells from differentiating while protecting the stem cells from direct contact with the feeder in an effort to prevent cross-contamination or passing nonhuman pathogens into the stem cells. Research is progressing with the development of a variety of protocols.
What is clone R?
CloneR™ is a defined, serum-free supplement designed to increase the cloning efficiency and single-cell survival of human embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells).
Is mTeSR serum-free?
mTeSR™1 is a highly specialized, serum-free, and complete cell culture medium. With pre-screened raw materials that ensure batch-to-batch consistency and robust feeder-free protocols for ES and iPS cell culture, mTeSR™1 provides more consistent cultures with homogeneous, undifferentiated phenotypes.
Does stem cell therapy work?
Stem cell treatment has achieved positive results in over 45% of patients, according to one trial. Patients saw improvement in less than 6 months, which compares quite well with back surgery that usually involves very long recovery times.
What is feeder-free conditions?
Therefore, to facilitate the development of clinical applications for hES cells, a feeder-free culture system, which includes the critical factors secreted by feeders or other activators of the same signaling pathways, needs to be identified.
What do feeder cells do?
Basically, feeder cells consist in a layer of cells unable to divide, which provides extracellular secretions to help another cell to proliferate. In this context, human stem and pluripotent cells play an important role, but the presence of feeder cells is necessary for these progenitor cells to grow and differentiate.