What is carboplatin and Alimta?
Carboplatin + Pemetrexed (Alimta®) (Carbo/Pem) is a Chemotherapy Regimen for Lung Cancer, Non-Small Cell Lung Cancer (NSCLC)
How effective is carboplatin for lung cancer?
Phase I and II trials of carboplatin as single-agent treatment for small-cell lung cancer resulted in overall response rates of approximately 60% for previously untreated patients and 17% for those who had received prior therapy.
How effective is pemetrexed and carboplatin?
Objective response rates were 26.8% for pemetrexed/oxaliplatin patients and 31.6% for pemetrexed/carboplatin patients. Median time to progression was 5.5 and 5.7 months for pemetrexed/oxaliplatin and pemetrexed/carboplatin, respectively. Median overall survival was 10.5 months for both treatment groups.
How many cycles of carboplatin can you have?
When you have carboplatin You might have carboplatin every 3 to 4 weeks. Each 3 or 4 week period is a cycle of treatment. You might have between 4 to 6 cycles.
Does ALIMTA shrink tumors?
Proven to help shrink tumors In a clinical trial, 48% of people experienced a reduction in tumor size in the ALIMTA + KEYTRUDA and platinum chemotherapy group compared to 19% in the ALIMTA and platinum chemotherapy group.
How long can you take ALIMTA?
You may stay on ALIMTA + KEYTRUDA for as long as your cancer remains stable or improves and you don’t have any unacceptable side effects (or up to 35 cycles, about 2 years for KEYTRUDA).
How long does chemo prolong life in lung cancer?
Chemotherapy (chemo) may prolong life in some lung cancer patients. According to a study reported in the Journal of the American Medical Association that looked at the role of chemotherapy at the end of life, chemo for some patients with a specific type of lung cancer prolonged their lives by two to three months.
What is the latest treatment for lung cancer?
Today, the U.S. Food and Drug Administration approved Lumakras (sotorasib) as the first treatment for adult patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation called KRAS G12C and who have received at least one prior systemic therapy.
What type of chemo is ALIMTA?
ALIMTA is a type of chemotherapy called an anti-folate. As a chemotherapy, it is believed to help to kill or slow the growth of cancer cells.
How often is ALIMTA given?
ALIMTA is usually given once every 21 days (3 weeks). away if you have any signs of infection, fever, bleeding, or severe tiredness during your treatment with ALIMTA. Kidney problems, including kidney failure. ALIMTA can cause severe kidney problems that can lead to death.
Will I lose my hair with carboplatin?
This treatment may cause hearing changes, including hearing loss. You may have ringing in the ears. This is called tinnitus. You may also become unable to hear some high-pitched sounds.
How quickly does carboplatin work?
How long does treatment take? Each dose, or cycle, of carboplatin takes 15 minutes to an hour. It may take longer if you are having carboplatin with other drugs. You’ll usually have one cycle of carboplatin every 21–28 days.
What are the uses of carboplatin and pemetrexed?
Carboplatin and pemetrexed are medications prescribed to treat certain types of cancer. They may be prescribed together or a patient may take only one of them. Carboplatin is typically used to treat ovarian cancer, however a doctor may also prescribe it for other types of cancer, such as lung, testicular, or bladder cancer.
Is Alimta a vesicant?
ALIMTA is not a vesicant. There is no specific antidote for extravasation of ALIMTA. To date, there have been few reported cases of ALIMTA extravasation, which were not assessed as serious by the investigator. ALIMTA extravasation should be managed with local standard practice for extravasation as with other non-vesicants.
Can Alimta cause hair loss?
Alimta® (pemetrexed) is a prescription chemotherapy medication, and hair loss is one of the possible side effects. In one clinical study, hair loss was reported in up to 7 percent of people who took Alimta alone. Even more people develop hair loss when Alimta is combined with other chemotherapy medications.