What is cardioprotective effect?
Medical Definition of cardioprotective : serving to protect the heart especially from heart disease cardioprotective effects of ACE inhibitors a cardioprotective agent.
What are the effects of flavonoids?
Many flavonoids are shown to have antioxidative activity, free radical scavenging capacity, coronary heart disease prevention, hepatoprotective, anti-inflammatory, and anticancer activities, while some flavonoids exhibit potential antiviral activities.
What is the purpose of flavonoids?
Flavonoids are structurally diverse secondary metabolites in plants, with a multitude of functions. These span from functions in regulating plant development, pigmentation, and UV protection, to an array of roles in defence and signalling between plants and microorganisms.
What are flavonoids in simple terms?
Flavonoids are a group of plant metabolites thought to provide health benefits through cell signaling pathways and antioxidant effects. These molecules are found in a variety of fruits and vegetables. Flavonoids are polyphenolic molecules containing 15 carbon atoms and are soluble in water.
What is a cardioprotective diet?
A cardioprotective diet (a healthy diet high in fibre, fruit and vegetables and oily fish) can help improve blood cholesterol and blood pressure and reduce your risk of having a stroke or heart disease. A high intake of fat and salt can increase your risk of having a stroke or heart disease.
Why is alcohol cardioprotective?
Apart from this, moderate ethanol increases PON1, an HDL-associated antiatherogenic enzyme, that has its cardioprotective action because it (1) hydrolyzes oxidized lipids in OxLDL in serum and macrophages, a prerequisite for the onset of atherosclerosis, (2) inhibits cholesterol uptake by macrophages from OxLDL [24.
What is Kaempferol good for?
Kaempferol reduces the risk of chronic diseases, especially cancer. Kaempferol augments human body’s antioxidant defense against free radicals. Kaempferol modulates apoptosis, angiogenesis, inflammation, and metastasis.
What are examples of flavonoids?
These 10 foods are some of the best sources of dietary flavonoids available:
- Berries. All berries contain flavonoids, but certain varieties are more potent than others.
- Red Cabbage. Another great dietary source of anthocyanidins is red cabbage.
- Onions.
- Kale.
- Parsley.
- Tea.
- Red Wine.
- Dark Chocolate.
How do flavonoids act as antioxidants?
Flavonoids are phenolic substances isolated from a wide range of vascular plants, with over 8000 individual compounds known. However, most interest has been devoted to the antioxidant activity of flavonoids, which is due to their ability to reduce free radical formation and to scavenge free radicals.
Which source of fat is cardioprotective?
The cardioprotective (Mediterranean) diet The Mediterranean diet is also based on a modified fat intake that is low in saturated fat, with partial replacement of saturated fat by monounsaturated fat. This type of advice has been shown to lower the incidence of CHD morbidity and mortality.
How much wine is cardioprotective?
Cardioprotective dosage of alcohol intake is considered to be 1 or two drinks per day for men and one drink per day for women [53, 65, 66].
What are the effects of flavonoids on lipids?
Flavonoids are potent antioxidants, free radical scavengers, and metal chelators and inhibit lipid peroxidation.
What is the generic structure of flavonoids?
Chemistry of flavonoids Generic structure and major classifications Flavonoids are low molecular weight polyphenolic sub- stances based on the flavan nucleus.29 Figure 1 shows the generic structure of flavonoids and the numbering system used to distinguish the carbon positions around the mole- cule.
What foods are the best sources of flavonoids?
Dietary intake of flavonoids range between 23 mg/day estimated in The Netherlands and 170 mg/day estimated in the USA. Major dietary sources of flavonoids determined from studies and analyses conducted in The Netherlands include tea, onions, apples, and red wine.
Where are flavonoids absorbed in the human body?
Flavonoids are absorbed from the gastrointestinal tracts of humans and animals and are excreted either unchanged or as flavonoid metabolites in the urine and feces. Flavonoids are potent antioxidants, free radical scavengers, and metal chelators and inhibit lipid peroxidation.