What did Angelika Amon research?
Amon’s research has investigated how cells control and organize the segregation of their chromosomes during cell division. More specifically, her research examines the regulation of exit from mitosis, the regulation of the meiotic cell cycle, and effects of aneuploidy on normal physiology and tumorigenesis.
How did Angelika Amon die?
Ovarian cancer
Angelika Amon/Cause of death
What phase do chromosomes separate?
anaphase
During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes. The chromosomes are separated by a structure called the mitotic spindle.
What’s the meaning of anaphase?
Anaphase is the fourth phase of mitosis, the process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes.
Where is a centrosome located?
cytoplasm
The centrosome is positioned in the cytoplasm outside the nucleus but often near to it. A single centriole is also to be found at the basal end of cilia and flagella.
Where is centrosome found?
The centrosome is located in the cytoplasm usually close to the nucleus. It consists of two centrioles — oriented at right angles to each other — embedded in a mass of amorphous material containing more than 100 different proteins.It is duplicated during S phase of the cell cycle.
What is the function of a chromatid?
Function of Chromatids It authorizes cells to store two copies of their information in preparation for cell division. This is important to make sure that daughter cells are healthy and fully functional, carrying a full complement of the parent cells DNA.
What is chromatid and chromatin?
As mentioned above, chromatin is composed of DNA and histones that are packaged into thin, stringy fibers. The chromatin undergoes further condensation to form the chromosome. A chromatid is either of the two strands of a replicated chromosome. Chromatids connected by a centromere are called sister chromatids.
What kind of research does Angelika Amon do?
The Amon lab studies cell growth and division. They investigate how macromolecule biosynthesis is coordinated with cell division, and how chromosome segregation is is regulated by intracellular and extracellular cues.
How old was Angelika Amon when she died?
Angelika Amon, professor of biology and a member of the Koch Institute for Integrative Cancer Research, died on Oct. 29 at age 53, following a two-and-a-half-year battle with ovarian cancer.
Who is the professor of cancer at MIT?
A molecular and cell biologist, Dr. Amon is the Kathleen and Curtis Marble Professor in Cancer Research and Professor of Biology at MIT. She received her B.S. from the University of Vienna and continued her doctoral work there under Professor Kim Nasmyth at the Research Institute of Molecular Pathology, receiving her Ph.D. in 1993.
When did Angelika Amon join Howard Hughes Medical Institute?
Amon has won a Presidential Early Career Award for Scientists and Engineers in 1998, was named an Associate Investigator at the Howard Hughes Medical Institute in 2000, and was the 2003 recipient of the National Science Foundation’s Alan T. Waterman Award.