What does cytotoxic drug mean in medical terms?
Listen to pronunciation. (SY-toh-TOK-sik AY-jent) A substance that kills cells, including cancer cells. These agents may stop cancer cells from dividing and growing and may cause tumors to shrink in size.
Is cytostatic chemotherapy?
Cytostatics are primarily used in cancer treatment. Within a chemotherapy they are applied as active agents to fight against the fast spreading tumor cells and thereby inhibiting tumor growth totally at best. Besides surgical therapy and irradiation, chemotherapy belongs to the three main pillars of cancer treatment.
Are antibiotics cytotoxic?
The cytotoxic antibiotics in current use in the United States include (with trade name and year of approval): bleomycin (Blenoxane, 1973), dactinomycin (Cosmegen, 1964), daunorubicin (Cerubidine, 1979), doxorubicin (Adriamycin, 1974), epirubicin (Ellence, 1999), idarubicin (Idamycin, 1990), plicamycin (previously known …
Is acyclovir cytotoxic?
The cytotoxic effects of acyclovir, which is a purine nucleoside analogue and is known as an antibiotic substance, were examined on three lines of rat skin fibroblast FR cells; normal FR cells, FRtk- cells which are deficient in the activity of thymidine kinase (tk) and FRtk-HSVtk+ cells which were prepared by …
Is amoxicillin cytotoxic?
The antibiotics Amoxicillin and Potassium Clavulanate showed cytotoxic effect to Perna perna mussels in the cytotoxicity assay by NRRT method. The drugs presented about four times more toxicity in association than when tested isolated.
What is cytostatic agent?
Listen to pronunciation. (SY-toh-STA-tik AY-jent) A substance that slows or stops the growth of cells, including cancer cells, without killing them. These agents may cause tumors to stop growing and spreading without causing them to shrink in size.
How does cytotoxic medication work?
Cytotoxic drugs work by interrupting cells at particular places in the growth cycle. 3 They are most likely to affect cells that are growing rapidly, for example, cancer cells, hair follicles, bone marrow, and cells lining the stomach and intestines.