How would you tell primary spermatocytes from spermatogonia in a histological slide?
Spermatogonia are large precursor cells and are always located along the basement membrane of the tubule. Primary spermatocytes have large, heterochromatic nuclei, and they are located between the basement membrane and the lumen of the tubule.
What is spermatogenesis in histology?
As mentioned above, spermatogenesis is the process by which sperm cell production occurs; the germ cells give rise to the haploid spermatozoa. Sperm production takes place inside the seminiferous tubules, which is a convoluted cluster of tubes located inside the testes.
How do you identify primary spermatocytes?
The first cells you’ll see nearest the edge of the tubule are called spermatogonia — descendants of the original germ cells. On the other side of the tight junctions you find primary spermatocytes, secondary spermatocytes, spermatids, and then finally mature sperm at the lumen, or center of the tubule.
How can you differentiate between Sertoli cells spermatogonia and primary spermatocytes?
The Sertoli cells have pale nuclei and dense nucleoli. The spermatogonia and the nuclei of the Sertoli cells lie on the basal membrane. The nuclei of these cells are pale, with prominent nuclolei. Primary spermatocytes, secondary spermatocytes, spermatids and spermatozoa are in the adluminal compartment.
What is a primary Spermatocyte?
Medical Definition of primary spermatocyte : a diploid spermatocyte that has not yet undergone meiosis.
Which cells are directly involved in spermatogenesis?
Sertoli cells are directly involved in spermatogenesis. They are also called “sustentacular cells” or “nurse cells”.
What is a primary spermatocyte?
What are the three stages of spermatogenesis?
Spermatogenesis can be divided into three phases: (1) proliferation and differentiation of spermatogonia, (2) meiosis, and (3) spermiogenesis, a complex process that transforms round spermatids after meiosis into a complex structure called the spermatozoon.
What are primary spermatocytes?
Spermatocytes are a type of male gametocyte in animals. They derive from immature germ cells called spermatogonia. They are found in the testis, in a structure known as the seminiferous tubules. Primary spermatocytes are diploid (2N) cells.
What cells produce primary spermatocytes?
The mitotic division of these produces two types of cells. Type A cells replenish the stem cells, and type B cells differentiate into primary spermatocytes.
What is primary spermatocyte?
primary spermatocyte the original large diploid cell into which a spermatogonium develops; it can later undergo the first meiotic division into the secondary spermatocyte. secondary spermatocyte a haploid cell produced by meiotic division of the primary spermatocyte; it can then develop into the spermatid.
What is primary spermatocytes and secondary spermatocyte?
There are two types of spermatocytes, primary and secondary spermatocytes. Primary spermatocytes are diploid (2N) cells. After meiosis I, two secondary spermatocytes are formed. Secondary spermatocytes are haploid (N) cells that contain half the number of chromosomes.
How are the primary and secondary spermatocytes formed?
Primary and secondary spermatocytes are formed through the process of spermatocytogenesis (Figure 3). Primary spermatocytes are diploid (2N) cells. After Meiosis I, two secondary spermatocytes are formed. Secondary spermatocytes are haploid (N) cells that contain half the number of chromosomes.
Where are spermatogenic cells located in the epithelium?
Spermatogenic cells include each of the stages between the spermatogonium and the mature spermatozoan. These cells appear in layers that represent advancing stages in their differentiation, with the least mature cells near the basal layer of the epithelium and the most mature cells near the luminal layer.
Why are Sertoli cells important to the spermatozoa?
Sertoli cells – (sustentacular cell) These cells are the spermatozoa supporting cells, nutritional and mechanical, as well as forming a blood-testis barrier. The cell cytoplasm spans all layers of the seminiferous tubule. The cells are named after Enrico Sertoli (1842 – 1910), and italian physiologist and histologist.
When do gonocytes turn into spermatogonial stem cells?
In humans at about 2 months of age, primordial germ cells (gonocytes) are replaced by adult dark (Ad) and pale (Ap) spermatogonia forming the spermatogonial stem cell (SSC) population that at puberty will commence differentiation into spermatozoa.