Why is sevoflurane better than desflurane?
Sevoflurane has a blood: gas partition coefficient of 0.65, which is slightly greater than desflurane. The major advantage over desflurane is the better scent. It is considered to be less airway irritation in LMA anesthesia with smooth induction and recovery.
Why does desflurane need a special vaporizer?
Desflurane’s unique characteristics (high volatility/moderate potency) require the use of a special vaporizer for proper utilization of this gas. Desflurane vaporizers are heated to 39 degrees C, which increases the vapor pressure in the sump to 1300mmHg, preventing the possibility of boiling in warm OR rooms.
What type of anesthesia is desflurane?
Desflurane belongs to the group of medicines known as general anesthetics. Inhaled desflurane is used to cause general anesthesia (loss of consciousness) before and during surgery in adults. It is also used as a maintenance anesthesia in adults and children after receiving other anesthetics before and during surgery.
What type of vaporizer is desflurane?
The Tec 6 desflurane vaporizer is not a variable bypass vaporizer, it is a gas-vapor blender.
How much does desflurane cost?
Table 1
| Desflurane | Sevoflurane | |
|---|---|---|
| Total cost | 21.05 | 4.69 |
| 4 L/min | ||
| Inhalational agent cost | 41.28 | 8.56 |
| CO2 absorbent cost | 0.2 | 0.2 |
What is the MAC of desflurane?
Background: The minimum alveolar concentration (MAC) of desflurane/oxygen is 7.25% in the 18-30-yr age group, and 6.0% in the 31-65-yr age group. The addition of 60% N2O reduces MAC to 4.0 and 2.83%, respectively.
When do you not use desflurane?
The use of desflurane is contraindicated in patients with known or suspected genetic susceptibility to malignant hyperthermia, in those whom general anesthesia is contraindicated, and those with known sensitivity to desflurane or to other halogenated agents.
Can desflurane be used for induction?
The FDA-approved indications for desflurane are induction or maintenance of anesthesia in adults. It may also be used to maintain anesthesia in pediatric patients following induction with agents other than desflurane. Desflurane is a racemic mixture of two enantiomers.
How is desflurane administered?
Desflurane is administered by inhalation. Desflurane should only be administered by persons trained in the administration of general anaesthesia using a vaporizer specifically designed and designated for use with desflurane.
What is sevoflurane used for?
Sevoflurane belongs to the group of medicines known as general anesthetics. Sevoflurane is used to cause general anesthesia (loss of consciousness) before and during surgery. It is inhaled (breathed in). Although sevoflurane can be used by itself, combinations of anesthetics are often used together.
Can we use isoflurane in sevoflurane vaporizer?
Using the halothane or isoflurane vaporizers at the 5% setting, the maximum sevoflurane concentrations achieved were 3.0% and 3.1%, respectively. The sevoflurane concentration was a maximum of 6% using the enflurane vaporizer set at 7%.
How much Sevoflurane is used during surgery?
Surgical levels of anesthesia can usually be achieved with concentrations of 0.5 – 3% sevoflurane with or without the concomitant use of nitrous oxide.
What’s the difference between desflurane and sevofluran anesthesia?
No difference between the two groups was found in pain, shivering, nausea, vomiting, and incidence of postoperative hemodynamic events. Patients who received desflurane had a shorter extubation and recovery time but similar intraoperative and postoperative incidence of complications compared with those who received sevoflurane.
What’s the blood pressure range for sevoflurane anesthesia?
Intraoperatively, mean arterial blood pressure (MAP) and heart rate (HR) were maintained within predetermined limits: desflurane and sevoflurane doses were adjusted to maintain the MAP within a range of 20% of preanesthesia level with HR <90 bpm.
What is the Mac range for desflurane anesthesia?
MAC range for sevoflurane and desflurane was 0.8–1.5. The end-tidal concentrations of the volatile anesthetics and the ETco 2 were monitored continuously. Throughout the study period, MAC was recorded in real-time for MAC-hour calculation (average MAC length of exposure).
How much Propofol does it take to induce anesthesia?
In all patients, anesthesia was induced with propofol (3 mg/kg), fentanyl (3 μg/kg), and vecuronium (0.1 mg/kg) with the patient breathing 100% O 2. After intubation of the trachea, mechanical ventilation was begun.