What does Lyme 41 kd IgG mean?

What does Lyme 41 kd IgG mean?

This particular marker is called 41 KD (IGG) Band and hence is a IgG antibody marker. IgG antibodies are a sign of an older infection. In contrast, IgM antibodies reflect a relatively recent infection. IgM antibodies usually disappear after eight weeks post-exposure. IgG remains in the serum for a very long time.

What is band 41 Lyme?

The 41 band indicates an antibody to the flagella 41 kDa protein and is nonspecific. The 31 kDa band represents the OSPA protein and is specific for just a few species of Borrelia, as is the 34 band OSPB, and 23 kDa OSPC. Some bands are Lyme Specific, some are not. For example, band 41 can represent Lyme spiroch.

What does 39 kd IgM band reactive mean?

Two types of antibodies are detected in the Western blot test. This particular marker is called 39 KD (IGM) and hence is a IgM antibody marker. IgM antibodies reflect a relatively recent infection. IgG antibodies in contrast are a sign of an older infection.

What bands are positive for Lyme?

Some Lyme specialists and scientists believe that there are five very specific bands on the Western blot test that are highly indicative of Lyme disease: band numbers 23, 31, 34, 39 and 93. If any of these bands are positive and the patient is experiencing symptoms of Lyme disease, they may feel treatment is warranted.

What does positive Lyme IgG mean?

A positive result means that Borrelia antibodies were found and that you may have had or have Lyme disease. False-positive results sometimes do occur. This means the test could say you have the infection when you don’t.

How long does Lyme IgG stay positive?

IgG antibodies are slower to develop, beginning to show 4-6 weeks after exposure and may peak 4-6 months after exposure. While IgM tends to be associated with an active infection, both IgM and IgG can persist in the blood for many years.

Is band 41 Lyme specific?

What is the significance of band 41 on the IgM and IgG Western blot? It is not Lyme specific and the CDC requires more bands to be present before a diagnosis. However, it is a band for bacteria so what else could cause that to be positive if not Lyme? The 41 kd band is often found on the Western blot.

What does a reactive Lyme test mean?

How often is Lyme test false positive?

While these labs strive for high sensitivity they do not outperform reference labs in finding Lyme disease. [6] Moreover, specificity as low as 43% is reported, indicating that 57% of results coming from such labs are false positives.

Can a positive Lyme test be something else?

Although it’s the most common way to check for Lyme disease, the ELISA test isn’t perfect. It can sometimes give false “positive” results. On the other hand, if you have it done too soon after you’ve been infected, your body may not have developed enough antibodies for the test to detect them.

What is normal range for Lyme disease?

Reference Range Normal levels vary depending on the laboratory assay performed, as follows. Borrelia burgdorferi antibody enzyme immunoassay (Lyme index value) : < 0.9 = negative. 0.91-1.09 = equivocal.

How long does IgG stay positive in Lyme?