What is EMA CO regimen?

What is EMA CO regimen?

Since the development of effective chemotherapy, high-risk GTN has become one of the most curable human malignancies [4]. EMA/CO (Etoposide, Methotrexate, Actinomycin D, Cyclophosphamide and Vincristine) is the most widely used primary combination therapy for high-risk GTN [5].

What is Chorioadenoma Destruens?

Listen to pronunciation. (KOR-ee-oh-A-deh-NOH-muh des-TROO-ens) A type of cancer that grows into the muscular wall of the uterus. It is formed after conception (fertilization of an egg by a sperm).

How is hydatidiform mole diagnosed?

Diagnosis of Hydatidiform Mole They suspect a hydatidiform mole based on symptoms, such as a uterus that is much larger than expected and a vaginal discharge of grapelike tissue. A pregnancy test is done. If women have a hydatidiform mole, results are positive, but no fetal movement and no fetal heartbeat are detected.

What is the choriocarcinoma?

(KOR-ee-oh-KAR-sih-NOH-muh) A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary.

Is leucovorin folic acid?

Leucovorin is in a class of medications called folic acid analogs. It works by protecting healthy cells from the effects of methotrexate or similar medications while allowing methotrexate to enter and kill cancer cells.

What is gestational trophoblastic tumor?

Gestational trophoblastic disease (GTD) is a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception. In gestational trophoblastic disease (GTD), a tumor develops inside the uterus from tissue that forms after conception (the joining of sperm and egg).

What is an invasive mole?

Invasive mole is penetration of molar tissue (complete or partial mole) into myometrium or uterine vasculature (1, 16, 19). Edematous villus and proliferative trophoblasts invade myometrium so they can be distinguished from choriocarcinoma. Pathologists mention the existence of villi in trophoblastic tissue (8, 12).

How is the H mole diagnosed and removed?

Treatment of Hydatidiform Mole A chest x-ray is taken to see whether the mole has spread to the lungs. The level of human chorionic gonadotropin in the blood is measured to determine whether the hydatidiform mole was completely removed.

What are the signs and symptoms of hydatidiform mole?

Symptoms

• Abnormal growth of the uterus, either bigger or smaller than usual.
• Severe nausea and vomiting.
• Vaginal bleeding during the first 3 months of pregnancy.

How is choriocarcinoma diagnosed?

Blood and urine tests. An exam to see if the cancer has spread to other parts of your body. Imaging tests such as CT, MRI, ultrasound, or X-ray.

What is the survival rate of choriocarcinoma?

Can doctors cure it? Doctors can almost always cure gestational choriocarcinoma with chemotherapy. The survival rates range from about 90 to 100% , depending on a person’s risk factors.