How many mL is 300 mcg of RhoGAM?
One syringe contains at least 1500 IU (300 mcg) of IgG antibodies to Rh0(D) in a 2 mL solution, sufficient to suppress the immune response to at least 15 mL of Rh-positive RBCs.
How many mL is a RhoGAM syringe?
DOSAGE AND ADMINISTRATION
| Dose | Indication | Notes |
|---|---|---|
| RhoGAM (300 µg) (1500 IU) | ≥ 2.5 mL Rh-positive red blood cells | Administer 20 µg of RhoGAM per mL of Rh-positive red blood cell exposure, rounding up to the next whole syringe. |
How much RhoGAM do you give?
This standard dose of Rho(D) immune globulin (300 mcg) covers FMH up to 15 mL of fetal red cells (30 mL of whole fetal blood). However, there are times when the additional dose is necessary due to massive red blood cell FMH and subsequent maternal immune response.
What is RhoGAM when and why is it used?
RhoGAM (rhod immune globulin human) is a sterilized solution made from human blood used to prevent an immune response to Rh positive blood in people with an Rh negative blood type. RhoGAM may also be used in the treatment of immune thrombocytopenic purpura (ITP).
How much RhoGAM should I take after delivery?
Usual (standard) dose after delivery of full-term infant is 1 vial; it must be given within 72 hours after delivery or miscarriage. If Rho(D) immune globulin is indicated before delivery, administer 1 vial (standard dose) at about 28 weeks’ gestation and give a second vial within 72 hours of delivery.
How fast do you push RhoGAM IV?
-Initial dose: 250 international units (50 mcg) per kg, IV, over 3 to 5 minutes; may be divided into 2 doses on separate days if desired.
Where do you inject RhoGAM?
RhoGAM is a prescription drug typically given by injection into a muscle — often in the backside, so just another indignity you’ll deal with while pregnant. It can also be given intravenously. Your doctor will decide what’s the appropriate dose for you. RhoGAM is effective for about 13 weeks.
How long is RhoGAM at room temperature?
If the reconstituted product is not used immediately, it may be stored at room temperature for up to 12 hours; do not freeze. Discard the reconstituted lyophilized product if not used within 12 hours of reconstitution. Use aseptic technique. WinRho SDF: Bring the solution to room temperature before use.
How do you calculate RhoGAM?
Calculations for Estimating the Number of Vials of Rhogam Needed:
- One 300 ml vial of RhIG will protect against 30 ml of D-positive fetal blood.
- The conversion factor used to indicate the volume of fetomaternal hemorrhage (as ml’s of whole blood) is: percent fetal red cells observed X 50.
Is RhoGAM given to mom or baby?
At delivery, if the newborn is Rh-positive, the mother will receive another dose of RhoGAM.” This last injection is given just in case there was any cross-contamination of blood from baby to mother during delivery.
What happens if a Rh positive mother gets RhoGAM?
RhoGAM is a sterilized solution made from human blood that contains a very small amount of Rh-positive proteins. These proteins keep your immune system from making permanent antibodies to Rh-positive blood. They do not hurt your baby.
How long does RhoGAM last in the body?