What causes Hypopigmented mycosis fungoides?
Hypopigmentation in MF has been proposed to be a result of an immune response originating from neoplastic cells or reactive immune cells [12]. However, we hypothesize that hypopigmentation is caused mainly by the active antitumor immune response.
How common is Hypopigmented mycosis fungoides?
HMF may account for 17% to 59% of all MF cases diagnosed during childhood. An analysis of 131 new cases of MF/Sézary syndrome (SS) in Singapore over a 5-year period reported a median age of 33 at the time of diagnosis, with a mean age of 36.3.
How do you treat Hypopigmented mycosis fungoides?
Phototherapy, especially Psoralen and ultraviolet, is the first-line treatment used widely for the treatment of rare hypopigmented variant of mycosis fungoides.
Is hypopigmentation contagious?
The exact cause is unknown, but it may be due to an autoimmune disorder or a virus. Vitiligo is not contagious. Treatment options may include exposure to UVA or UVB light and depigmentation of the skin in severe cases.
How do you treat Hypopigmented skin?
Hypopigmentation is a condition in which the skin is lighter in color than normal. Treating hypopigmentation may involve the use of topical corticosteroids or tars, light or laser treatment, or surgical skin grafting. Melanin is the substance that gives skin its color or pigment.
Are there any cases of hypopigigmented mycosis fungoides?
Background: Only five cases of purely macular hypopigmented mycosis fungoides have been published in the literature. These patients all had clinical evidence of disease 7 months to 10 years prior to histologic diagnosis, suggesting that this clinical presentation of mycosis fungoides is easily misdiagnosed.
How long does it take for mycosis fungoides to develop?
Mycosis fungoides can present as a chronic itch, even before there are clinical signs of disease. Classic MF progresses slowly over years from patches to plaques and may eventually form tumours. Most patients are diagnosed with early-stage disease.
What kind of lymphoma causes hypopigmentation?
Since the above differentials were not consistent with the patient’s presentation, an uncommon cause of hypopigmentation was considered: cutaneous T-cell lymphoma, known as mycosis fungoides. Hypopigmented lesions are themselves a rare manifestation of this disease, typically seen in patients of darker skin types.1
Which is the subtipo of micose fungoide?
A micose fungoide hipocromiante pode ser considerada um subtipo da micose fungoide, apresentando algumas características peculiares que contrastam com os achados da forma clássica da micose fungoide. A maioria dos pacientes com micose fungoide hipocromiante são mais jovens que aqueles acometidos pela micose fungoide clássica.
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