What kind of drug is DALVANCE?

What kind of drug is DALVANCE?

Dalvance is a prescription medicine used to treat the symptoms of Acute Bacterial Skin Structure Infections such as MRSA. Dalvance may be used alone or with other medications. Dalvance belongs to a class of drugs called Glycopeptides.

What bacteria does DALVANCE cover?

DALVANCE ® (dalbavancin) for injection is indicated for the treatment of adult and pediatric patients with acute bacterial skin and skin structure infections (ABSSSI) caused by designated susceptible strains of Gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin- …

How long does it take for DALVANCE to work?

Dalvance is bactericidal against Staphylococcus aureus (including methicillin-resistant strains), Streptococcus pyogenes, Streptococcus agalactiae, and the Streptococcus anginosus group. Dalvance time to peak is 0.5 to 1 hour.

Is DALVANCE antibiotic?

Dalvance (dalbavancin) is an antibiotic that fights bacteria. Dalvance is used to treat severe skin infections caused by bacteria.

How is DALVANCE administered?

DALVANCE is administered via intravenous infusion, using a total infusion time of 30 minutes to minimize the risk of infusion-related reactions. Rapid intravenous infusions of DALVANCE can cause reactions that resemble “Red-Man Syndrome,” including flushing of the upper body, urticaria, pruritus, and/or rash.

Does DALVANCE cover MRSA?

Dalbavancin (Dalvance) and oritavancin (Orbactiv) are semi-synthetic lipoglycopeptides with potent in vitro activity against multidrug-resistant gram-positive organisms, including MRSA.

How do you administer DALVANCE?

How do you mix DALVANCE?

Using a suitable gauge needle and syringe, each 500 mg vial of DALVANCE should be reconstituted by slowly adding 25 mL of Sterile Water for Injection, USP, or 5% Dextrose Injection, USP. Gently roll the vial to ensure all surfaces containing DALVANCE have been wetted.

What is DALVANCE used for?

This medication is used to treat serious bacterial infections of the skin. It works by stopping the growth of bacteria.

Is DALVANCE refrigerated?

Storage of Reconstituted or Diluted DALVANCE Does not require refrigeration. Once reconstituted or diluted into an intravenous bag or bottle as previously described, DALVANCE may be stored in a refrigerator between 2 to 8°C (36 to 46°F), or at controlled room temperature 20 to 25°C (68 to 77°F) for up to 48 hours.

What does Dalvance ( dalbavancin ) do for You?

Dalvance (dalbavancin) is an antibacterial medication. It kills bacteria by preventing them from making their own protective covering. What is Dalvance (dalbavancin) used for? Dalvance (dalbavancin) is given through intravenous (IV) infusion over 30 minutes.

How many mg of Dalvance should I take per day?

Convenient storage and stability 1. In patients with renal impairment whose known creatinine clearance is less than 30 mL/min and who are not receiving regularly scheduled hemodialysis, the recommended regimen of DALVANCE is 1125 mg, administered as a single dose, or 750 mg followed one week later by 375 mg.

When to use Dalvance in patients with ABSSSI?

DALVANCE IS INDICATED for the treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) due to designated susceptible Gram-positive pathogens. See full Indication and Usage below . DALVANCE is contraindicated in patients with known hypersensitivity to dalbavancin.

What are the risks of Dalvance in the elderly?

DALVANCE is substantially excreted by the kidney, and the risk of adverse reactions may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection in this age group.