What is the difference between nodal and extranodal lymphoma?

What is the difference between nodal and extranodal lymphoma?

Extranodal lymphoma, by definition, involves sites other than lymph nodes, spleen, thymus and the pharyngeal lymphatic ring. Involvement of the spleen in HD is considered as nodal disease but in the case of non-Hodgkin lymphoma (NHL) the spleen is regarded as an extranodal site.

What is extranodal B cell lymphoma?

Extranodal marginal zone B-cell lymphoma, also known as mucosa-associated lymphoid tissue (MALT) lymphoma: This is the most common type of marginal zone lymphoma. It starts in places other than the lymph nodes (extranodal). There are gastric and non-gastric MALT lymphomas.

Is bone marrow considered extranodal?

Extranodal disease with a predilection for certain sites is common; the liver, kidney, lung, bone, and bone marrow are commonly involved [3]. These sites also tend to be involved where nodal disease is ex- tensive.

Is extranodal extension bad?

Extranodal extension of lymph node metastasis is a marker of poor prognosis in oesophageal cancer: a systematic review with meta-analysis.

What does extranodal extension present mean?

Extranodal extension refers to the growth of a nodal cancer metastasis beyond the confines of the capsule of a lymph node into adjacent tissues. Less preferred synonyms include extranodal spread, extracapsular extension, or extracapsular spread.

What is the definition of primary extra nodal lymphoma?

Primary extra-nodal (PE)-NHL is defined as the first occurrence of NHL in any extra-nodal tissues or organs whose main lesions originate from lymph nodes.

Are there any extra nodal lymphoma in the buttock?

The most commonly involved extra-nodal organs are the gastrointestinal tract, Waldeyer ring, and nasal cavity, while primary extra-nodal non-Hodgkin lymphoma (PE-NHL) arising from the spleen, soft tissue, mediastinum, and other tissues is rare. PE-NHL arising in buttock soft tissue is extremely rare.

Are there any cases of soft tissue lymphoma?

Seven cases of primary soft tissue lymphoma were found. Among these, 3 cases were found in lower extremities, 2 cases in the psoas muscle, 1 case in the back, and 1 case in the sternocleidomastoid muscle. [5] Therefore, this type of lymphoma is likely to be misdiagnosed.

Where does the lymphoid go in the buttocks?

There are 2 channels of lymphatic drainage in the buttocks that allow lymphoid tissue from gluteal lymph nodes to flow into inguinal nodes and, eventually, into the lumbar trunk. [10]