Is dichloroacetic acid a strong acid?

Is dichloroacetic acid a strong acid?

Chemistry and occurrence As an acid with a pKa of 1.35, pure dichloroacetic acid is classed as a strong organic acid; it is very corrosive and extremely destructive to tissues of the mucous membranes and upper respiratory tract via inhalation.

How is dichloroacetic acid manufactured?

The most common production method for dichloroacetic acid is the hydrolysis of dichloroacetyl chloride, which is produced by the oxidation of trichloroethylene. It can also be obtained by hydrolysis of pentachloroethane with 88–99% sulfuric acid or by oxidation of 1,1-dichloroacetone with nitric acid and air.

How do you make dichloroacetic acid?

Are there any side effects of dichloroacetate for cancer?

An extensive body of literature describes anticancer property of dichloroacetate (DCA), but its effective clinical administration in cancer therapy is still limited to clinical trials. The occurrence of side effects such as neurotoxicity as well as the suspicion of DCA carcinogenicity still restrict …

Is there a cure for cancer in Canada?

Cure For Cancer Found In Canada – Dichloroacetate (DCA) That’s exactly what a Dr. Michelakis and his team at the University of Alberta are claiming. The drug, dichloroacetate (DCA) can alter the metabolism of cancer cells and thus causes them to age and be destroyed. It’s important to note that it kills the cancer cells but only the bad ones.

Is there a cure for cancer with DCA?

Michelakis have been researching the effects of DCA on non-human subjects since 2007. It has been proven successful and consistently reduced the cancerous cells. Since then, and perhaps more importantly the team has accomplished the same results in human trials.

Why is DCA dichloroacetate an orphan drug?

This is where DCA, dichloroacetate comes into play. DCA is an “orphan drug”, meaning it is old, off-patent drug originally used for lactic acidosis, and genetic mitochondrial disease. (8,9) Since DCA is off-patent and not profitable, drug companies are unlikely to fund large scale clinical trials.