Does dyslipidemia cause cardiovascular disease?
Dyslipidemia is recognized as a prominent risk factor for cardiovascular (CV) disease. 1 Current guidelines focus on lowering low-density lipoprotein cholesterol (LDL-C) with a statin in both primary and secondary intervention settings.
Is dyslipidemia a risk factor for heart failure?
Dyslipidemia is a well-established risk factor for coronary heart disease (CHD),2 and results from clinical trials of lipid-modifying therapy demonstrate that treatment with statins also decreases the incidence of HF.
Is dyslipidemia coronary heart disease?
Dyslipidemia is a primary, widely established as an independent major risk factor for coronary artery disease (CAD) and may even be a prerequisite for CAD, occurring before other major risk factors come into play. [9] Studies have reported higher prevalence of lipid abnormalities among Asians compared with non-Asians.
What diseases are associated with dyslipidemia?
Severe or untreated dyslipidemia can lead to other conditions, including coronary artery disease (CAD) and peripheral artery disease (PAD). Both CAD and PAD can cause serious health complications, including heart attacks and strokes.
Is dyslipidemia same as hypercholesterolemia?
Hypercholesterolemia is most commonly, but not exclusively, defined as elevated levels of low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (HDL-C); an alternative term is dyslipidemia, which encompasses elevated triglycerides, low levels of HDL-C, and qualitative lipid …
Is dyslipidemia considered a disease?
Dyslipidemia is an abnormal amount of lipids (e.g. triglycerides, cholesterol and/or fat phospholipids) in the blood. Dyslipidemia is a risk factor for the development of atherosclerotic cardiovascular disease (ASCVD). ASCVD includes coronary artery disease, cerbrovascular disease, and peripheral artery disease.
How does dyslipidemia cause heart failure?
Dyslipidemia is known to promote atherosclerosis. It is a complex disease and is a major risk factor for adverse cardiovascular events. High levels of low‐density lipoprotein (LDL) and low levels of high‐density lipoprotein (HDL) are associated with myocardial infarction (MI) and stroke.
What does dyslipidemia mean?
Dyslipidemia, defined as elevated total or low-density lipoprotein (LDL) cholesterol levels, or low levels of high-density lipoprotein (HDL) cholesterol, is an important risk factor for coronary heart disease (CHD) and stroke.
Which lipids can cause heart disease?
High levels of LDL cholesterol and triglycerides, and low levels of HDL cholesterol are linked to heart disease. High levels of LDL cholesterol, often called the “bad” cholesterol, are associated with heart disease. LDL cholesterol can stick to artery walls causing the formation of blockages or plaques.
What is the main cause of dyslipidemia?
Dyslipidemia is classified into primary and secondary dyslipidemia. Primary causes are single or multiple gene mutations that result in either overproduction or defective clearance of triglycerides (TG) and low-density lipoprotein (LDL), or in underproduction or excessive clearance of high-density lipoprotein (HDL).
Can dyslipidemia cause hypertension?
Dyslipidemia, a strong predictor of cardiovascular disease,5 causes endothelial damage,6–8 and the loss of physiological vasomotor activity that results from endothelial damage may become manifested as increased blood pressure (BP).
How does dyslipidemia affect the body?
This can cause heart disease, heart attack, peripheral artery disease (reduced blood flow in the limbs, usually the legs), or stroke. Low levels of HDL and high levels of triglycerides can also increase fat build-up in the arteries.
How does dyslipidemia affect the risk of cardiovascular events?
Dyslipidemia is known to promote atherosclerosis. It is a complex disease and is a major risk factor for adverse cardiovascular events. 8, 9, 10 High levels of low‐density lipoprotein (LDL) and low levels of high‐density lipoprotein (HDL) are associated with myocardial infarction (MI) and stroke.
What is the prevalence of dyslipidemia in Iran?
Darroudi et al. have recently reported the prevalence of dyslipidemia among a subsample of Iranian adults to be 83 and 87% in the total population and CVD patients, respectively [ 8 ]. CVD is a chronic non-communicable disease and one of the most important causes of death and disability [ 9 ].
How many people die each year from heart disease?
According to the Centers for Disease Control and Prevention (CDC), heart disease kills over 610,000 people in the United States every year—or 1 in 4 deaths. On the other hand, stroke kills 140,000 Americans each year—1 in 20 deaths. Dyslipidemia is one of the major causes of heart disease and stroke.
What is the Cox regression model for dyslipidemia?
Cox regression model and 95% confidence interval (CI) were used to evaluate the association of dyslipidemia and its components with CVD incidence.