What is methimazole tablet used for?
METHIMAZOLE (meth IM a zole) lowers the amount of thyroid hormone made by the thyroid gland. It treats hyperthyroidism (where the thyroid gland makes too much hormone). It also is used before thyroid surgery or radioactive iodine treatment.
What are the side effects of transdermal methimazole in cats?
The most common side effect is upset of the digestive tract. Up to 20% of cats may experience nausea, vomiting, loss of appetite and just not feel well. Usually this is self-limiting and most cats stop vomiting and begin to feel better without any change to the medication.
What is methimazole transdermal?
Methimazole is a medication that is used in veterinary medicine to treat hyperthyroidism because it reduces the amount of thyroid hormone being produced by the thyroid gland. The medicine that’s used in the topical gel formulation is the same as that in the commercially manufactured tablets.
Is transdermal methimazole effective for cats?
Methimazole administered as a transdermal gel appears to be a safe and effective option for the treatment of hyperthyroid cats.
How does methimazole make you feel?
Minor adverse reactions include skin rash, urticaria, nausea, vomiting, epigastric distress, arthralgia, paresthesia, loss of taste, abnormal loss of hair, myalgia, headache, pruritus, drowsiness, neuritis, edema, vertigo, skin pigmentation, jaundice, sialadenopathy, and lymphadenopathy.
Will I gain weight on methimazole?
After methimazole treatment, body weight was initially increased (0–8 weeks), subsequently plateaued (8–24 weeks), and gradually decreased in the later period (24–52 weeks) despite the decreased food intake. The measured REE was 40% higher than the predicted REE at baseline, and it gradually decreased after treatment.
How long does transdermal methimazole take to work in cats?
In cats, oral methimazole is rapidly absorbed, with: An oral bioavailability of 93% Maximal serum concentrations seen within 1.5 hours.
Is methimazole safe to touch?
The answer from drug-safety experts is that methimazole in any form should be handled with caution. The medication impedes the body from using iodine to make thyroid hormone, thereby inhibiting synthesis of the hormone.
How fast does methimazole work?
Results: Within 3 weeks, 40.2% of patients responded to 10 mg of methimazole and 77.5% responded within 6 weeks.
How long does it take transdermal methimazole to work in cats?
Do you gain weight on methimazole?
Which is the correct dosage form for methimazole?
One of the dosage forms available for Methimazole is Transdermal Gel. When a patient won’t take their prescribed medication in an oral liquid, capsule or other dosage form, a transdermal gel may be an appropriate course of therapy. Wedgewood Pharmacy compounds more than 30 preparations into a transdermal gel.
What’s the difference between methimazole and transdermal gel?
Methimazole is a medication used to treat hyperthyroidism (overactive thyroid) in pets, but especially cats. The medication used in the transdermal gel is the same as the tablets manufactured commercially but the difference is the delivery of the medication. Transdermal means across the skin.
Are there any side effects to taking methimazole?
Methimazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: skin rash. itching. abnormal hair loss. upset stomach. vomiting. loss of taste.
Is the hepatic toxicity of methimazole more cholestatic?
The hepatic toxicity of methimazole is more of a cholestatic process, as compared to allergic hepatitis seen in propylthiouracil, and recovers slowly after discontinuing the drug. (3) Teratogenicity Methimazole can cross the placental membrane readily due to its insignificant protein binding.