Which drugs are factor Xa inhibitors?
Factor Xa Inhibitors
- apixaban.
- Arixtra.
- betrixaban.
- Bevyxxa.
- edoxaban.
- Eliquis.
- fondaparinux.
- rivaroxaban.
Are apixaban and rivaroxaban the same?
Are Xarelto and Eliquis the Same Thing? Eliquis (apixaban) and Xarelto (rivaroxaban) are anticoagulants (blood thinners) used to reduce blood clotting and systemic embolism in patients with nonvalvular atrial fibrillation. Xarelto is often used in patients undergoing knee or hip replacement surgery.
What drugs are DOACs?
Direct oral anticoagulants (DOACs)—dabigatran (Pradaxa), rivaroxaban (Xarelto), apixaban (Eliquis), edoxaban (Savaysa), and betrixaban (Bevyxxa) are anticoagulation pharmacotherapy used for the prevention of thrombosis in several cardiovascular contexts.
Is apixaban an anticoagulant?
Apixaban is a type of medicine known as an anticoagulant, or blood thinner. It makes your blood flow through your veins more easily. This means your blood will be less likely to make a dangerous blood clot.
How does apixaban inhibit XA?
Rivaroxaban, apixaban and edoxaban directly bind to the active site of factor Xa, thus inhibiting both free and clot-associated factor Xa. Indirect inhibitor such as fondaparinux binds to ATIII, causing conformational change that results in the inhibition of factor Xa without having any effect on factor IIa.
Is eliquis a factor Xa inhibitor?
ELIQUIS is an oral, reversible factor Xa inhibitor indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
Why is apixaban better than rivaroxaban?
We demonstrate that dabigatran, rivaroxaban, and apixaban have similar effectiveness in the reduction of stroke or systemic embolism. Furthermore, apixaban appears to be associated with a lower risk of major bleeding, whereas rivaroxaban is associated with a higher risk of major bleeding.
Which is safer apixaban or rivaroxaban?
Bottom line: In routine practice, apixaban is more effective and safer than rivaroxaban with a lower rate of strokes, systemic embolism, and major bleeding.
Is rivaroxaban a DOAC?
Why is it called DOAC?
What are DOACs? The term DOAC (pronounced ‘DOH-ack’) stands for ‘Direct Oral AntiCoagulant’ and refers to a group of new anticoagulant medications. An anticoagulant is a medica- tion that either treats or prevents blood clots, often called a ‘blood thinner’.
Is apixaban better than rivaroxaban?
What class is apixaban?
Apixaban is in a class of medications called factor Xa inhibitors. It works by blocking the action of a certain natural substance that helps blood clots to form.
What is the generic name for apixaban for DVT?
Generic name: apixaban (a PIX a ban) Brand name: Eliquis, Eliquis Starter Pack for Treatment of DVT and PE Dosage forms: oral tablet (2.5 mg; 5 mg) Drug class: Factor Xa inhibitors
What’s the generic name for the factor Xa inhibitor apixaban?
Apixaban. Generic name: apixaban (a PIX a ban) Brand name: Eliquis, Eliquis Starter Pack for Treatment of DVT and PE. Dosage forms: oral tablet (2.5 mg; 5 mg) Drug class: Factor Xa inhibitors. Medically reviewed by Drugs.com on June 11, 2021. Written by Cerner Multum. Uses. Warnings.
What are the potential drug interactions with apixaban?
Apixaban Drug Interaction Potential 1 The absorption of apixaban is mediated by P-glycoprotein (P-gp). 2 The metabolism of apixaban is mediated by CYP3A4. 3 Agents that interfere with both P-gp and CYP3A4 are likely to cause more significant interactions…
What is the dosage of apixaban for PE?
Generic name: apixaban (a PIX a ban) Brand name: Eliquis, Eliquis Starter Pack for Treatment of DVT and PE. Dosage forms: oral tablet (2.5 mg; 5 mg) Drug class: Factor Xa inhibitors. Medically reviewed by Drugs.com on June 11, 2021. Written by Cerner Multum. Uses. Warnings. Dosage.