What is typical for leprosy face lion face?
Lepromatous leprosy presents with widespread symmetric facial distribution of lesions leading to coarsening of features (leonine facies). The earlobes and nose are especially enlarged and infiltrated. Intranasal and paranasal sinus involvement is common and occurs after cutaneous nasal involvement.
What are leonine features?
Leonine facies (LF) is defined as displaying facial features similar to that of a lion with prominent convexities and furrowed creases. LF develops in a very small population of patients with cutaneous T-cell lymphoma.
What are the two types of leprosy?
Leprosy has traditionally been classified into two major types, tuberculoid and lepromatous. Patients with tuberculoid leprosy have limited disease and relatively few bacteria in the skin and nerves, while lepromatous patients have widespread disease and large numbers of bacteria.
What is globi in leprosy?
The histiocytes may show vacuolated or frothy cytoplasm with a grayish-blue tinge (on H&E) due to clusters (globi) of leprosy bacilli. With modified Ziehl-Neelsen stain (Wade-Fite stain), the bacilli can be visualized in large numbers in histiocytes surrounding cutaneous nerves, blood vessels, and eccrine glands.
What is a leonine face?
Leonine facies is a facies that resembles that of a lion. It is seen in multiple conditions and has been classically described for lepromatous leprosy as well as Paget’s disease of bone.
What is lion face?
Leontiasis ossea, also known as leontiasis, lion face or lion face syndrome, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones.
What are leonine facies?
Leonine facies is a face that resembles that of a lion. It is a rare clinical presentation and corresponds to the morphologic manifestation of diffuse dermal infiltration of the face. It has been classically described for lepromatous leprosy.
What is PB disease?
Paucibacillary (PB), or tuberculoid, Hansen’s disease is characterized by one or a few hypopigmented or hyperpigmented skin macules that exhibit loss of sensation (anesthesia) due to infection of the peripheral nerves supplying the region.
What is Fite stain?
Modified Ziehl-Neelsen Stain (Wade-Fite Stain): Mycobacterium leprae are much less acid- and alcohol-fast as compared to mycobacterium tuberculosis. The mycolic acid coat of leprosy bacilli is less strong and is easily decolorized by the standard Ziehl-Neelsen technique.
What is Lucio phenomenon?
Lucio phenomenon is a severe complication of multibacillary leprosy that is marked by blue hemorrhagic plaques and necrotic ulcerations. The bacilli may extend to the endothelial cells along with the appearance of necrotic epidermis and vasculitis with thrombus formation and endothelial proliferation.
What is Paucibacillary?
Paucibacillary patients are those who are skin smear negative and show no evidence of more advanced disease on biopsy. Multibacillary patients are those who are skin smear positive and/or have a biopsy indicating more advanced disease.
What is lion face syndrome?
Jump to navigation Jump to search. Leontiasis ossea, also known as leontiasis, lion face or Lion Face Syndrome, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones.
What causes leprosy disease?
Leprosy is a chronic, progressive bacterial infection caused by the bacterium Mycobacterium leprae. It primarily affects the nerves of the extremities, the skin, the lining of the nose, and the upper respiratory tract. Leprosy is also known as Hansen’s disease.
What does leprosy look like?
The symptoms of leprosy are irregular spots and patches on the skin. These are either lighter colored than the surrounding skin, or reddish in color. On those patches, hair will fall out, and they will feel numb to the patient.