What is the difference between darbepoetin and epoetin?
Darbepoetin is currently marketed by its manufacturer as having “increased potency and longer half-life” compared with epoetin, which purportedly “allows for less-frequent dosing than the previous standard of care.”3 However, until recently, there have been few reports of clinical trials directly comparing darbepoetin …
Is Epogen and epoetin the same?
Epogen and Procrit are both epoetin alfa, but they are marketed by two different pharmaceutical companies. The FDA approved epoetin alfa in June 1989.
What is the difference between Epogen and Aranesp?
Epoetin alfa (Retacrit, Procrit, Epogen) is a glycoprotein that stimulates red blood cell production; whereas, darbepoetin alfa (Aranesp) stimulates erythropoiesis by the same mechanism as endogenous erythropoietin.
How much Epogen should I take?
If the hemoglobin level exceeds 10 g/dL, reduce or interrupt the dose of Epogen, and use the lowest dose of Epogen sufficient to reduce the need for RBC transfusions. The recommended starting dose for adult patients is 50 to 100 Units/kg 3 times weekly intravenously or subcutaneously.
Is darbepoetin better than erythropoietin?
Safety profile of DA-α and EPO was similar. Conclusion: Our study results demonstrate that DA-α given at a reduced dose frequency is as effective and well tolerated as EPO for treating renal anemia in pre-dialysis patients with CKD.
What is the difference between epoetin alfa and beta?
Epoetin-alpha and epoetin-beta resemble each other with respect to molecular characteristics and pharmacokinetic data, although epoetin-beta has a higher molecular weight, a lower number of sialylated glycan residues and possibly slight pharmacokinetic advantages such as a longer terminal elimination half-life.
Is retacrit the same as Epogen?
Retacrit cannot be interchanged with Epogen at the pharmacy level; the physician must specifically order Retacrit. Retacrit (epoetin alfa-epbx), from Hospira, and Epogen, (epoetin alfa), from Amgen, are both erythropoiesis-stimulating agents (ESA) used to help improve red blood cell production.
Is Epogen given IM or SQ?
Epogen can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection. When giving subcutaneous injections, follow your healthcare provider’s instructions about changing the site for each injection.
Is Aranesp better than Epogen?
There are no clinically significant differences in the safety and efficacy of epoetin alfa (Epogen, Procrit) and darbepoetin alfa (Aranesp), the two drugs most commonly used to treat anemia in cancer patients undergoing chemotherapy or radiation treatments, according to a new report by the Agency for Healthcare …
What is another name for Retacrit?
Retacrit (epoetin alfa-epbx) Injection is an erythropoiesis-stimulating agent (ESA) indicated for treatment of anemia due to chronic kidney disease (CKD) in patients on dialysis and not on dialysis; zidovudine in patients with HIV-infection; the effects of concomitant myelosuppressive chemotherapy, and upon initiation.
Is retacrit the same as EPOGEN?
Is EPOGEN given IM or SQ?