What causes Saber shins?
Saber shins are a malformation of the tibia that presents with anterior bowing of the tibia, usually caused by congenital syphilis or rickets. If caused by syphilis, saber shins typically appear along with other symptoms of syphilis, such as Hutchinson’s teeth and mulberry molars.
What bones are often affected by Paget’s disease?
Paget’s disease of bone can affect 1 bone or several bones. Commonly affected areas include the pelvis, spine and skull.
Does Paget’s disease make you tired?
When Paget’s disease is active in several bones, overactive osteoclasts may release enough calcium from the bone as they break it down to cause an elevated calcium level in the blood. This rare complication can lead to a number of symptoms, including: Fatigue. Weakness.
What is the first line treatment for Paget disease?
Bisphosphonates are first-line therapy for Paget’s disease, and the advent of the new bisphosphonates permits a dramatic improvement in treatment.
Why is my shin bone sharp?
Medial tibial stress syndrome, or shin splints, is the inflammation of the tendons, muscles, and bone tissue around the tibia. People describe shin splint pain as sharp, or dull and throbbing.
What is a Sabre sword?
sabre, also spelled saber, heavy military sword with a long cutting edge and, often, a curved blade. Most commonly a cavalry weapon, the sabre was derived from a Hungarian cavalry sword introduced from the Orient in the 18th century; also a light fencing weapon developed in Italy in the 19th century for duelling.
What does Paget’s disease of the bone look like?
A doctor can usually diagnose Paget’s disease by looking at an X-ray. An affected bone appears larger and more dense than usual. It can have a deformed shape. In the very early stages of Paget’s disease, when there is just overactive absorption going on, it can look like there is a hole in the bone.
What does Paget’s disease feel like?
Paget’s disease of the nipple always starts in the nipple and may extend to the areola. It appears as a red, scaly rash on the skin of the nipple and areola. The affected skin is often sore and inflamed, and it can be itchy or cause a burning sensation. The nipple can sometimes be ulcerated.
How long can you live with Paget’s disease?
The 5-year survival rate for a patient with Paget disease and sarcoma is 5-7.5%; however, it may be as high as 50% for those who undergo operative tumor ablation and chemotherapy before metastases occur. The 5-year survival rate for elderly patients with primary nonpagetic sarcoma is 37%.
What is the life expectancy of someone with Paget’s disease?
In that study, the British General Practice Research Database identified 2465 patients diagnosed with Paget’s disease of bone from 1988 to 1999; retrospective review indicated that 5-yr survival was 67% in patients with Paget’s disease compared with 72% in control patients.
Is Paget disease curable?
There’s currently no cure for Paget’s disease of bone, but treatment can help relieve the symptoms. If you do not have any symptoms, your doctor may suggest keeping an eye on your condition and delaying treatment until any problems occur.
Why do my shin bones feel bumpy?
The process of remodeling is the removal of part of the bone that is not strong enough, and replacing it with stronger bone to cope with the increased demand. This explains the bumpy feeling on the shin bone during assessment.
Are there specific symptoms of Paget disease of tibia?
No periosteal reaction or bone destruction. There were no specific symptoms localizing to the left tibia. The combination of the x-ray and nuclear imaging findings lead to a diagnosis of Paget disease.
What kind of skin cancer does Paget’s disease have?
Extramammary Paget’s disease (EMPD) is a rare skin cancer of the genital region in which cancer cells with enlarged nuclei and pale cytoplasm are scattered singly in the affected epidermis. These cancer cells, called Paget cells, contain mucin, which is never found in normal epidermis.
What causes a saber shin in the tibia?
Saber shin. Saber shin is a malformation of the tibia. It presents as a sharp anterior bowing, or convexity, of the tibia. Causes. It can result from syphilis, yaws, Paget’s disease of bone, Vitamin D deficiency, or Weismann-Netter-Stuhl syndrome.
What does saber shin mean in medical terms?
Saber shin is a malformation of the tibia. It presents as a sharp anterior bowing, or convexity, of the tibia. It can result from syphilis, yaws, Paget’s disease of bone, vitamin D deficiency or Weismann-Netter–Stuhl syndrome.