Is labetalol similar to metoprolol?
Labetalol is as safe and effective as metoprolol in the treatment of patients with mild to moderate hypertension.
Does IV labetalol affect heart rate?
This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure.
How long does IV labetalol last?
It has an onset of action within 2 to 5 minutes, reaches its peak effects at 5 to 15 minutes, has an elimination half-life of 5.5 hours, and a duration of action up to four hours.
Is IV labetalol short acting?
IV labetalol has an onset of action of 2 to 5 minutes and peaks within 5 to 15 minutes. Its duration of action is dose dependent, ranging from 2 to 18 hours.
Which is stronger labetalol or metoprolol?
There was little difference between the drugs in the influence on blood pressure, but metoprolol and propranolol were significantly more effective than labetalol in lowering the heart rate.
What is a substitute for labetalol?
Conclusions: Nicardipine offers an alternative to labetalol with similar tolerability and appears to provide a smoother blood pressure control compared to labetalol.
Is labetalol more alpha or beta?
Labetalol is more potent at beta that at alpha 1 adrenoceptors in man; the ratio of beta-alpha antagonism is 3:1 after oral and 6.9:1 after intravenous administration.
When do you give IV labetalol?
Severe Hypertension If it is essential to reduce the blood pressure quickly a dose of 50 mg should be given by I.V. injection (during 1 minute) and, if necessary, be repeated at 5-minute intervals until a satisfactory response occurs. The total dose should not exceed 200 mg.
How is IV labetalol given?
An alternative method of administering labetalol is intravenous infusion of a solution made by diluting the contents of two ampoules (200mg) to 200ml with Sodium Chloride and Dextrose Injection BP or 5% Dextrose Intravenous Infusion BP. The resultant infusion solution contains 1mg/ml of labetalol hydrochloride.
What is labetalol IV used for?
Labetalol injection is used to treat severe high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
Which is the most effective beta blocker?
A cardioselective beta-blocker such as bisoprolol or metoprolol succinate will provide the maximum effect with the minimum amount of adverse effects.
What is a good replacement for labetalol?
What are the uses of IV labetalol?
Commonly used brand name (s)
Is metoprolol given for high BP?
Metoprolol is a beta-blocker used to treat high blood pressure, heart pain, abnormal rhythms of the heart, and some neurologic conditions. Other beta-adrenergic blockers include propanolol ( Inderal, Inderal LA, Innopran XL ), atenolol ( Tenormin ), and timolol ( Blocadren ).
Can metoprolol and propranolol be taken together?
Brief Answer: Detailed Answer: Metoprolol is a selective beta blocker , acting at certain sites/points in the heart and blood vessels. Propranolol is non selective, meaning that it acts at the same sites plus additional areas. Typically two beta blockers are not usually given together.
What is labetalol used to treat?
Labetalol is a medication used to treat high blood pressure and in long term management of angina.