What is a lichenoid lesion?
The term lichenoid reaction (lichenoid eruption or lichenoid lesion) refers to a lesion of similar or identical histopathologic and clinical appearance to lichen planus (i.e., an area which resembles lichen planus, both to the naked eye and under a microscope).
Is lichenoid reaction precancerous?
Classically it has been considered a precancerous condition, although the malignant transformation does not exceed 1% of cases. In recent years the differentiation between oral lichen planus (OLP) and oral lichenoid lesions (OLL) has become important, since the latter might have a greater malignant potential.
Is lichenoid inflammation cancerous?
The most important complication of lichenoid reactions is the possibility of malignant transformation. That is why it has been considered a precancerous condition. Although the malignant transformation rate varies widely in the literature, from 0.4 to 6.5 percent, in most studies it does not exceed 1%.
How long does Lichenoid keratosis last?
This lesions can persist for 3 to 12 months. They present as reddish brown to brown hyperpigmented papules or plaques. Dermatoscopy may show features of lentigo or flat seborrhoeic keratosis like lesion, often with a classic moth bitten border and comedo-like opening.
Is Lichenoid keratosis itchy?
Lichenoid keratosis, also known as, keratosis lichenoides chronica is a condition where, usually, a solitary brown lesion turns red and becomes itchy. These lesions usually appear in an area that is exposed to the sun. They generally appear most on the forearms, hands or chest of middle aged white women.
What does lichenoid mean?
It is a symbiotic fungus/alga characterised by flat-topped organisms. Lichenoid skin disorders got their name from their appearance – also flat topped and often somewhat scaly. They are characterised by a particular type of inflammation found on histology.
How can you tell the difference between lichen planus and lichenoid reaction?
Oral lichen planus (OLP) and oral lichenoid reaction (OLR) are clinically and histopathologically similar diseases. Whereas OLP is a consequence of T cell mediated autoinflammatory process to a still unknown antigen, OLR might be caused by drugs, dental restorative materials and dental plaque.
How are lichenoid reactions treated?
What is the treatment for an oral lichenoid eruption?
- Potent topical steroids such as clobetasol propionate.
- Other topical treatments such as tacrolimus.
- Oral medications including oral steroids such as prednisone (prednisolone).
What causes a lichenoid reaction?
Lichenoid reaction (LR) is an adverse effect which may be caused by systemic administration of drugs including antihistamine, corticosteroid and some other triggers. The prevalence of LR has been reported to be approximately 2.4% in the general population and occurs in women three times more than in men.
What causes lichenoid reaction?
How long do oral lichenoid reactions last?
Oral lichenoid contact reaction to cinnamon flavored chewing gum. Within 10 days of discontinuing the gum, the lesion completely resolved.
What are oral lichenoid lesions?
Oral lichenoid lesion (OLL) is a chronic inflammatory lesion of the oral mucosa that occurs as an allergic response to dental materials, to use of certain medications, in patients with graft-vs-host disease (GVHD), in patients with systemic diseases, e.g., chronic hepatitis C[1] and patients vaccinated against …
What causes lichenoid inflammation?
The exact cause of lichenoid keratosis isn’t known. It may be due to an inflammatory reaction. This happens when your immune system mistakenly attacks the skin. This reaction may be triggered by excess sun or UV light exposure, skin irritation, and some medications.
Which is the most common drug associated with lichenoid like eruptions?
Medications commonly reported to trigger a lichenoid drug eruption include: Antihypertensives – ACE inhibitors, beta-blockers, nifedipine, methyldopa. Diuretics – hydrochlorothiazide, frusemide, spironolactone.
What drugs cause lichenoid reaction?
Medications commonly reported to trigger a lichenoid drug eruption include:
- Antihypertensives – ACE inhibitors, beta-blockers, nifedipine, methyldopa.
- Diuretics – hydrochlorothiazide, frusemide, spironolactone.
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Phenothiazine derivatives.
What triggers lichen planus?
Lichen planus occurs when your immune system attacks cells of the skin or mucous membranes. It’s not clear why this abnormal immune response happens. The condition isn’t contagious. Lichen planus can be triggered by: Hepatitis C infection. Flu vaccine. Certain pigments, chemicals and metals.
What causes lichen planus outbreaks?
Causes of Oral Lichen Planus. The exact cause of oral lichen planus isn’t known, but certain things can trigger an outbreak or a worsening of the symptoms. Allergic reactions to products dentists use to perform dental procedures, mouth injuries and infections and certain medications can spark the development of the condition.
Does lichen planus affect the tongue?
Lichen planus of the mouth most commonly affects the inside of the cheeks, gums and tongue. Oral lichen planus is more difficult to treat and typically lasts longer than skin lichen planus. Fortunately, most cases of lichen planus of the mouth cause minimal problems.
What is lichenoid keratosis?
Lichenoid keratosis is a skin condition that typically occurs as a single, small, raised plaque, thickened area, or papule. It’s also referred to as: benign lichenoid keratosis. lichen planus-like keratosis.