How to make paracetamol syrup?

How to make paracetamol syrup?

For solution (2), dissolve 12.5 mg of 4-aminophenol R and 12.5 mg of paracetamol RS in about 20 ml of solvent mixture, and dilute to 50 ml with the solvent mixture. Dilute 5 ml of this solution to 50 ml with the solvent mixture.

What is paracetamol Paediatric syrup?

About paracetamol for children It’s often used to treat headaches, stomach ache, earache, and cold symptoms. It can also be used to bring down a high temperature (fever). It’s available as tablets or as a syrup.

How to prepare paediatric paracetamol elixir?

1. Paracetamol. 2.5 gm.
2. Ethanol. 10 ml. Propylene Glycol.
3. 10 ml. Conc. Mixed Fruit Juice. 2.5 ml.
4. Chloroform Spirit. 2 ml.
5. Sucrose Syrup. 28 ml. Annatto.
6. Different Concentration. Glycerin Q.S. Up To 100 ml.

How do you make a syrup?

It is prepared by dissolving 85 g of sucrose in enough purified water to make 100 mL of syrup. The resulting preparation generally requires no additional preservation if it is to be used soon; in the official syrup, preservatives are added if the sucrose concentration is less than 85% or syrup is to be stored.

How is paracetamol made?

Paracetamol is made by reacting 4-aminophenol with ethanoic anhydride (more commonly called acetic anhydride). This reaction forms an amide bond and ethanoic acid as a by- product. When the reaction is complete the paracetamol is then isolated and purified.

What ingredients are in paracetamol?

The active substance is paracetamol. Each tablet contains 500mg of paracetamol. The other ingredients are, maize starch, potassium sorbate, purified talc, stearic acid, povidone, and soluble starch.

What is Paediatric syrup?

Grilinctus Paediatric Syrup is a combination medicine that effectively relieves symptoms of common cold such as blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness.

Which syrup is best for fever in child?

Trusted and effective relief for children. BENYLIN® For Children All-In-One® COLD AND FEVER Syrup is all-in-one solution that combines trusted BENYLIN® ingredients with a great tasting bubble gum flavour. Relieve your kids’ COLD & FLU symptoms with 1 simple solution.

What is the difference between syrup and elixir?

Syrup is concentrated, viscous, aqueous solution of sugar or a sugar substitute with or without flavor and medical substance. Elixirs are clear, pleasantly flavored, sweetened hydro alcoholic liquids intended for oral use.

What is a use of paracetamol elixir formulation?

Paediatric Paracetamol Elixir (“Paracetamol Elixir”) contains paracetamol to relieve pain and reduce high temperatures. Paracetamol Elixir can be used in babies and children for the treatment of mild or moderate pain and feverishness, and also in babies who develop fever after vaccination.

What is the composition of syrup?

Syrups can be made by dissolving sugar in water or by reducing naturally sweet juices such as cane juice, sorghum juice, maple sap or agave nectar. Corn syrup is made from corn starch using an enzymatic process that converts it to sugars.

What is Gomme syrup made of?

WHAT IS GUM SYRUP? Gum syrup is a rich simple syrup (2:1 sugar:water) combined with gum Arabic, an all-natural resin harvested from the Acacia tree and found primarily in Northeast Africa.

How much paracetamol is in a paediatric oral solution?

DEFINITION • Paediatric Paracetamol Oral Solution is a solution containing 2.4% w/v of Paracetamol in a suitable flavoured vehicle. • Paediatric Paracetamol Oral Solution should not be diluted.

How is a paracetamol syrup a model drug?

This is one of the concepts of mixed-solvency. This same concept has been explored to formulate the syrups (solutions) of poorly water-soluble drug Paracetamol (as a model drug). For this, the blends containing solubilizers from the category of hydrotropes, co solvents and water soluble solids were employed.

How is the pH of paracetamol syrup determined?

Determination of pH: The pH of the developed paracetamol syrup formulations were determined using digital pH meter (Cyber Scan 510, Eutech Instruments Singapore) and were found almost neutral. The pH of the developed paracetmol syrup formulation FP1 and FP2 were 7.01, 7.02, respectively.

How to make paracetamol syrup with aspartum?

Dissolve 120 kgs of Paracetamol in 180 Kgs. Of P.G and heat to mix it properly until a clear solution is prepared, then add it to the bulk batch. Dissolve 0.150 kgs of Aspartum in 5 Ltrs of Purified water and add to the bulk batch.