How is thymol synthesized?

Industrially thymol is synthesized by liquid phase alkylation of m-cresol over activated alumina at 360 °C and 50 atm pressure using isopropyl alcohol (19) and in the gas phase over supported metal sulfates (20) or gamma alumina (7) using propylene as alkylating agent.

What type of compound is thymol?

Thymol is a phenol that is a natural monoterpene derivative of cymene. It has a role as a volatile oil component. It is a member of phenols and a monoterpenoid. It derives from a hydride of a p-cymene.

What is the Iupac name for thymol?

IUPAC Name	5-methyl-2-propan-2-ylphenol
Alternative Names	THYMOL 2-Isopropyl-5-methylphenol 5-Methyl-2-isopropylphenol
Molecular Formula	C10H14O
Molar Mass	150.221 g/mol
InChI	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3

Is thymol ionic or covalent?

Property Name	Property Value	Reference
Covalently-Bonded Unit Count	1	Computed by PubChem

Is thyme and thymol the same?

Thymol (10-64%) is one of the major constituent of essential oils of thyme (Thymus vulgaris L., Lamiaceae), a medicinal plant with several therapeutic properties. This plant, native to Mediterranean regions, is commonly used as a culinary herb and also with a long history of use for different medicinal purposes.

What does thymol mean?

: a crystalline phenol C10H14O of aromatic odor and antiseptic properties found especially in thyme oil or made synthetically and used chiefly as a fungicide and preservative.

What is the purpose of thymol?

Thymol improves digestion by relaxing smooth muscles, prevents menstrual cramps, attenuates respiratory problems and is an active ingredient used in food flavorings, topical ointments, various soaps, toothpastes, shampoos, deodorants and mouthwashes (Shapiro et al., 1994; Manou et al., 1998).

Is thymol a terpene?

Thymol, carvacrol, linalool, linalyl acetate, citronellal, piperitone, menthol, and geraniol are examples of terpenoids (Nazzaro et al., 2013). Terpenoids exhibited antimicrobial activity against variety of pathogens which is reported by many workers.

Why is thymol used in mouthwash?

Thymol is an antiseptic with antibacterial and antifungal activity. It is used as a mouthwash or gargle for oral hygiene and for refreshing the mouth, for treating sore throat and for minor mouth inflammation.

Can you ingest thymol?

Thymol resembles phenol in its systemic actions but less toxic due to its lower solubility. Ingestion may cause burning pain in the oesophagus, nausea, abdominal pain, vomiting, dizziness, convulsions, coma, cyanosis, central hyperactivity (e.g., talkativeness), cardiac and respiratory arrest.

Does thyme fight viruses?

Thyme EO and extracts show diverse antiviral activity against such viruses as influenza virus, HSV-1, HSV-2, and HIV-1.

How is thymol soluble in water at neutral pH?

Thymol is only slightly soluble in water at neutral pH, but it is extremely soluble in alcohols and other organic solvents. It is also soluble in strongly alkaline aqueous solutions due to deprotonation of the phenol . Thymol has a refractive index of 1.5208 and an experimental dissociation exponent ( p Ka) of 10.59 ± 0.10.

Why is thymol used as an antifungal in plants?

The antifungal nature of thymol against some fungi that are pathogenic to plants is due to its ability to alter the hyphal morphology and cause hyphal aggregates, resulting in reduced hyphal diameters and lyses of the hyphal wall.

How is thymol related to the anesthetic propofol?

Chemistry. Thymol has a refractive index of 1.5208 and an experimental dissociation exponent ( pKa) of 10.59±0.10. Thymol absorbs maximum UV radiation at 274 nm. Thymol is chemically related [clarification needed] to the anesthetic propofol .

Which is better for gingivitis chlorhexidine or thymol?

When used to reduce plaque and gingivitis, thymol has been found to be more effective when used in combination with chlorhexidine than when used purely by itself. Thymol is also the active antiseptic ingredient in some toothpastes, such as Johnson & Johnson ‘s Euthymol.