What is rapid mixer granulator?
Rapid mixer granulator is used for granulation in pharmaceutical manufacturing. It is used to mix the pharmaceutical ingredients and make the granules before compression and also called a high shear mixer. Impellers and chopper are mainly responsible for wet granulation in the rapid mixer granulator.
How do I calculate the capacity of my rapid mixer granulator?
For this, first, calculate the bulk density of powder to be mixed, then it multiplies by the capacity in liters (provided by the vendor), for, eg. Working capacity in a liter is 600 liter, and its working volume is 80% means 480 liters and bulk density is 0.5; then capacity in kgs is 480X0. 5= 240 kg.
What is the function of rapid mixer granulator?
Rapid Mixer Granulator is used to mix various ingredients and make the granules before condensing. It is used during many processes of manufacturing granulating of the powder in the Pharmaceutical industry, chemical industry, cosmetic manufacturing industry, generally dry and wet mixing industry.
How many types of RMG are there?
Mixing Chambers in Rapid mixer granulator is of 3 types Conical shaped , Domed shape , and Circular shaped although the basic aim behind all the shapes is to eliminate the dead points and wall adhesion i.e.the powder may not adhere to wall from where it cannot detach leading to inefficient granulation as well as mixing …
How do you use a rapid mixer granulator?
Start the agitator by setting the timer in the panel. After achieving the desired specific end point (Ampere Load) given in BMR, stop the operation and open the discharge valve with the help of knob provided on the panel.
How does a fluid bed granulator work?
Granulation in a fluidized bed granulator is achieved by suspending the powder in the air of the fluidized bed and then spraying the binder solution from nozzles that are either positioned above or below the powder bed depending on the type of the granulator.
How does a high shear granulator work?
High shear granulation is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. A binder liquid is fed to the powder particles in a closed container with blending tools and a chopper. Dense granules are formed through the liquid and solid bridges that result.
How is equipment occupancy calculated?
For example maximum occupancy for 200 litre equipment shall be calculated as 200 litre x 0.5 gm/ml = 100.00 Kg.
What is the end point of RMG?
Endpoint can be defined as a target particle size mean or distribution. a) Power Consumption. Power consumption of the mixer motor for end-point determination and scale-up is widely used because the measurement is economical, does not require extensive mixer modifications and is well correlated with granule growth.
What is role of purging air in RMG?
What is Purging Air in RMG? Generally, purging air is used to flush the industrial process equipment with clean air. Purging Air helps to keep the surfaces of RMG (Granulation Machine) clean and help in maintaining its effective performance.
What is a fluid bed granulator?
Fluidized bed granulator is one of the commonly used processing equipment in the pharmaceutical industries. It is a multi-purpose equipment in that mixing, granulation and drying are all carried out in the same equipment. The equipment operates in a bubbling bed regime.
What is high speed granulator?
A high-shear granulator or high-shear mixer uses a rotating impeller or high-speed rotor (or both) to create flow and shear. High-shear granulation is an effective way to turn powders into dense granules for tableting or coating.
What to consider when importing a rapid Mixer granulator?
Whenever you want to import pharmaceutical machines such as rapid mixer granulators/ high shear mixers, there are some obvious things you must consider. These include: Identify reputable and trusted rapid mixer granulator manufacturers. Shipping and logistics such as mode of shipment, taxes, shipping cost, etc.
Which is better high shear mixer or rapid mixer?
Granules produced by high shear mixer exhibit better general flow properties than those from fluidized bed granulator. In comparison to fluidized bed granulator, rapid mixer granulator is a simpler and easily cleanable machine, which complies with GMP requirements.
Which is the best granulator for wet granulation?
Rapid Mixer Granulator (RMG) We are one of the pioneer Pharmaceutical Machinery Manufacturers from India, We manufacture Rapid Mixer Granulator which is used in Pharma Industry for Wet Granulation, it is also known as High Shear Mixer.
What should I know about High Shear Mixer granulator?
Other aspects here may include position and rotating speed of both the chopper and impeller. In short, the design of every component and part of high shear mixer granulator will affect performance, efficiency, safety and reliability of the machine. Therefore, it is the first thing you must evaluate.