Can you take statins every other day?
5. The cholesterol-lowering action of alternate-day statins is as effective as daily dosing in many individuals. 6. To maintain the same degree of decrease in LDL-C when giving the statins on alternate days, the dose of the statins frequently needs to be increased.
Is 40mg of simvastatin too much?
Dosage. The usual dose for adults is between 10mg and 40mg once a day. People with very high cholesterol levels may be prescribed a higher dose of 80mg a day. Your dose depends on the reason for taking it, your cholesterol levels, and what other medicines you’re taking.
How long does it take for simvastatin to get out of your system?
Most short-acting statins have a half-life of 6 hours. A medication’s half-life is the time that it takes for the body to process and remove half of the medication.
Can you take a break from statins?
It’s possible for some people to stop taking statins safely, but it can be especially risky for others. For instance, if you have a history of heart attack or stroke, it’s not recommended that you stop taking these drugs. This is because you’re more likely to have another such problem when you discontinue statins.
Can you take statins once a week?
Conclusion: Once-weekly low-dose rosuvastatin is an effective and well-tolerated lipid-lowering therapy option for patients not at LDL goal and previously unable to tolerate statins because of a history of myalgias.
Can simvastatin make you gain weight?
The use of statins may be connected to weight gain, but there’s no clinical evidence as to why this weight gain occurs.
What medications should not be taken with simvastatin?
Do not use more than 20 mg per day of simvastatin together with amiodarone (Cordarone®), amlodipine (Norvasc®), lomitapide (Juxtapid™), or ranolazine (Ranexa®). When used together with higher doses of simvastatin, these medicines may increase your risk of muscle injury and could result in kidney problems.
Is 10mg of simvastatin effective?
Reductions in plasma total and LDL cholesterol were significantly greater with 5 mg simvastatin (16 and 23%) compared to 10 mg pravastatin (12 and 18%; p < or = 0.01). The efficacy of 10 mg simvastatin in lowering these lipid parameters was also superior (19 vs. 11% and 27 vs. 17%, respectively; p < or = 0.01).
Is simvastatin 40 mg safe?
The present results provide further evidence of the safety of long-term treatment with simvastatin 40 mg daily. The risk of myopathy was rare, with an incidence of less than 0.1% over 5 years, and there was no evidence that simvastatin 40 mg daily causes clinical hepatitis.
What are the most common side effects of simvastatin?
The most common statin side effects include:
- Headache.
- Difficulty sleeping.
- Flushing of the skin.
- Muscle aches, tenderness, or weakness (myalgia)
- Drowsiness.
- Dizziness.
- Nausea or vomiting.
- Abdominal cramping or pain.
Can you cut simvastatin in half before intake?
I would like to start with only 20 mg, but would need to cut them in half. Is there any problem with taking them once they have been cut in half? You are wondering if you can split simvastatin tablets. the answer is yes.
Can you split a statin pill in half?
Several studies suggest that most statins can be split in half without any loss of effectiveness.
Are there any side effects to taking simvastatin?
The main study for Simvastatin was the 4S trial which proved that the incidence rate for side effects at 40 mg of Simvastatin was 1 in 2,220 prescriptions. What is interesting is that the incidence rate in the placebo group was 1 in 2,223. Also muscle pain is a very common complaint and is a symptom of many conditions.
How long does a 40 mg simvastatin stay in your system?
Also muscle pain is a very common complaint and is a symptom of many conditions. Ed is correct about the half life, a normal 40 mg dose is out of your system within a day. Also, any side effects are usually gone in a couple days or a week at most.