What is the current prognosis for patients with glioblastoma multiforme?

What is the current prognosis for patients with glioblastoma multiforme?

Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor with an extremely poor prognosis in spite of aggressive treatment, consisting of surgery followed by chemoradiation and adjuvant chemotherapy [1, 2]. The estimated median survival in cases with GBM is about 12–16 months [3, 4].

What is the current 5 year survival of patients with glioblastoma multiforme GBM )?

The five-year survival rate for glioblastoma patients is only 6.8 percent, and the average length of survival for glioblastoma patients is estimated to be only 12 to 18 months. Survival rates and mortality statistics for GBM have been virtually unchanged for decades.

How fast does glioblastoma grow back after radiation?

However, we now know that GBM is a heterogeneous group of tumors (it behaves differently in different people) and the time when it comes back or recurs can vary. In the majority of patients it has a tendency to recur within 6-8 months. However, this can be either shorter or longer in a small proportion of patients.

What are the final stages of glioblastoma multiforme?

These symptoms include drowsiness, headaches, cognitive and personality changes, poor communication, seizures, delirium (confusion and difficulty thinking), focal neurological symptoms, and dysphagia. Some patients may have several of these symptoms, while others may have none.

What happens as glioblastoma progresses?

Armstrong: Glioblastoma is a fast-growing brain cancer. As it progresses, it develops infiltrative tumor that extends from the primary site, resembling threads of a spider’s web. Depending on where the tumor is located, it can’t always be removed entirely by surgery.

What happens at the end of glioblastoma?

How long is end of life glioblastoma?

The EOL may range from days to weeks, generally within three months from death [12]. In this phase, medical therapy and cares are aimed to reduce the symptom burden and to maintain the patient’s Quality Of Life (QOL) [9].